Many contemporary philosophers of mind disagree with substance dualism, saying that despite the failure of physical theories of mind, substance dualism cannot be advocated, because it faces more serious problems than physical theories, lacking compatibility with philosophical arguments and scientific evidence. Regardless of the validity of the arguments in support of substance dualism, it is demonstrated in this article that this theory is coherent, with no philosophical or scientific problems. The main arguments of opponents of substance dualism are explained and (...) criticized in this respect. Based on this, it becomes clear that the interaction of soul and body has a reasonable philosophical explanation, the problem of the pairing of soul and body, although it may not have a scientific explanation, it has a philosophical and theological solution, the principle of the physical causal closure lacks conclusive reasons and cannot reject the existence of the soul, the existence of the soul does not contradict the theory of evolution, the dependence of the soul on the brain is compatible with its independence, and finally, the principle of simplicity does not make any problem for accepting the substance dualism. (shrink)