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Evolving Concepts of 'Hierarchy' in Systems Neuroscience

In Fabrizio Calzavarini & Marco Viola (eds.), Neural Mechanisms: New Challenges in the Philosophy of Neuroscience (2021)

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  1. Evolving Concepts of Functional Localization.Joseph B. McCaffrey - 2023 - Philosophy Compass 18 (5):e12914.
    Functional localization is a central aim of cognitive neuroscience. But the nature and extent of functional localization in the human brain have been subjects of fierce theoretical debate since the 19th Century. In this essay, I first examine how concepts of functional localization have changed over time. I then analyze contemporary challenges to functional localization drawing from research on neural reuse, neural degeneracy, and the context-dependence of neural functions. I explore the consequences of these challenges for topics in philosophy of (...)
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  • Descriptive multiscale modeling in data-driven neuroscience.Philipp Haueis - 2022 - Synthese 200 (2):1-26.
    Multiscale modeling techniques have attracted increasing attention by philosophers of science, but the resulting discussions have almost exclusively focused on issues surrounding explanation (e.g., reduction and emergence). In this paper, I argue that besides explanation, multiscale techniques can serve important exploratory functions when scientists model systems whose organization at different scales is ill-understood. My account distinguishes explanatory and descriptive multiscale modeling based on which epistemic goal scientists aim to achieve when using multiscale techniques. In explanatory multiscale modeling, scientists use multiscale (...)
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