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  1. The Death of the Cortical Column? Patchwork Structure and Conceptual Retirement in Neuroscientific Practice.Philipp Haueis - 2021 - Studies in History and Philosophy of Science Part A 85:101-113.
    In 1981, David Hubel and Torsten Wiesel received the Nobel Prize for their research on cortical columns—vertical bands of neurons with similar functional properties. This success led to the view that “cortical column” refers to the basic building block of the mammalian neocortex. Since the 1990s, however, critics questioned this building block picture of “cortical column” and debated whether this concept is useless and should be replaced with successor concepts. This paper inquires which experimental results after 1981 challenged the building (...)
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  • The Search of “Canonical” Explanations for the Cerebral Cortex.Alessio Plebe - 2018 - History and Philosophy of the Life Sciences 40 (3):40.
    This paper addresses a fundamental line of research in neuroscience: the identification of a putative neural processing core of the cerebral cortex, often claimed to be “canonical”. This “canonical” core would be shared by the entire cortex, and would explain why it is so powerful and diversified in tasks and functions, yet so uniform in architecture. The purpose of this paper is to analyze the search for canonical explanations over the past 40 years, discussing the theoretical frameworks informing this research. (...)
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