: In 1878's ‘How to Make Our Ideas Clear’, Peirce states that truth is the predestinate opinion, or that which is fated to be ultimately agreed to by all who investigate. Later in his life, though, he would claim both that truth is what would be believed if we could figure out the right method of inquiry and that, instead of affirming that truth is the predestinate opinion in 1878, he ought to have affirmed that truth is what would be (...) believed if inquiry were carried sufficiently far. The aim of this paper is to provide an account of why the early Peirce endorses the claim that truth is the predestinate opinion and why the late Peirce is compelled to modify that position. I argue that Peirce's early statement that truth is the predestinate opinion is motivated by his theory that all mental action is of the nature of a valid inference and that the later modification of his view is partly motivated by his rejection of that theory. (shrink)

Nicholas Rescher embraces a more objectivist, realist, analytic pragmatism than the pragmatism which has been in vogue in the last two decades. He rejects any pragmatism for which there is no truth, reality, or objectivity but only conversations or solidarity within this or that vocabulary. Rescher has argued that pragmatism, far from being anti-realist, provides the only good argument for realism and for our ability to operate the causal model of inquiry about the real world. I examine this kind of (...) pragmatist argument, point out its pitfalls, and argue that Rescher avoids them. (shrink)

Any description of the emergence and evolution of different types of meaning processes (semiosis, sensu C.S.Peirce) in living systems must be supported by a theoretical framework which makes it possible to understand the nature and dynamics of such processes. Here we propose that the emergence of semiosis of different kinds can be understood as resulting from fundamental interactions in a triadically-organized hierarchical process. To grasp these interactions, we develop a model grounded on Stanley Salthe's hierarchical structuralism. This model can be (...) applied to establish, in a general sense, a set of theoretical constraints for explaining the instantiation of different kinds of meaning processes (iconic, indexical, symbolic) in semiotic systems. We use it to model a semiotic process in the immune system, namely, B-cell activation, in order to offer insights into the heuristic role it can play in the development of explanations for specific semiotic processes. (shrink)

The purpose of this thesis is to provide a robust epistemological justification for Evidence Based Medicine (EMB), and thereby to demonstrate the epistemological short comings of Complementary and Alternative Medicine (CAM). CAM has received support from both philosophers, such as Rorty and Feyerband, and the Sociology and Anthropology of Medicine. The thesis will thus review both the internal coherence and the application of non-realist arguments, and counter non-realism with the realist epistemology and philosophy of science that is represented by C.S. (...) Peirce’s pragmatism. Rorty and Feyerabend and others have developed radical forms of scientific antirealism in the latter 20th century. Subsequently, sociologists developed even more intractable forms of anti-realism, which they applied to the social study of science. This approach served to challenge the legitimacy of orthodox scientific practice (including EMB). A practical expression of this controversy was immediately identified in the question of the role of scientific authority in a democratic society. That question was immediately applied to the status of alternative medical systems and their legitimacy vis-a-vis EBM in terms of the controversy over what has come to be termed "medical pluralism": If scientific medicine has no particular authority, should other, medical systems, epistemically incompatible with EBM, be made available as well? The thesis will suggest that non-realism is in fact a marginal position within the philosophy of science. Scientists, medical researchers and medical practitioners may thus appeal to the philosophy of science in order to justify their authority in the face of challenges from CAM. However, it will be suggested that they are frequently ill-served by a reliance on a simplistic understanding of the philosophy of Karl Popper. An alternative will be proposed in the philosophy of C. S. Peirce. His pragmatism offers to medical research and medical practice a way of understanding and justifying the scientific process, a justification of realism in the face of non-realism, and a resource for the criticism of CAM and medical pluralism, as at once epistemologically ill grounded and potentially dangerous to patients and the general public. (shrink)

Since the term ‘pragmatism’ was first coined, there have been debates about who is or is not a ‘real’ pragmatist, and what that might mean. The division most often drawn in contemporary pragmatist scholarship is between William James and Charles Peirce. Peirce is said to present a version of pragmatism which is scientific, logical and objective about truth, whereas James presents a version which is nominalistic, subjectivistic and leads to relativism. The first person to set out this division was in (...) fact Peirce himself, when he distinguished his own ‘pragmaticism’ from the broad pragmatism of James and others. Peirce sets out six criteria which defines ‘pragmaticism’: the pragmatic maxim; a number of ‘preliminary propositions’; prope-positivism; metaphysical inquiry; critical common-sensism; and scholastic realism. This paper sets out to argue that in fact James meets each of these criteria, and should be seen as a ‘pragmaticist’ by Peirce’s own lights. (shrink)