In several applications of sequent calculi going beyond pure logic, an introduction of suitably defined rules seems to be more profitable than addition of extra axiomatic sequents. A program of formalization of mathematical theories via rules of special sort was developed successfully by Negri and von Plato. In this paper a general theorem on possible ways of transforming axiomatic sequents into rules in sequent calculi is proved. We discuss its possible applications and provide some case studies for illustration.