In his review, Walter (2012) links conceptual perspectives on empathy with crucial results of neurocognitive and genetic studies and presents a descriptive neurocognitive model that identifies neuronal key structures and links them with both cognitive and affective empathy via a high and a low road. After discussion of this model, the remainder of this comment deals more generally with the possibilities and limitations of current neurocognitive models, considering ways to develop process models allowing specific quantitative predictions.