Changes brought by the rise of the global economy and the end of the Cold War era have resulted in industry, government, and university rethinking their roles vis-à-vis research and development, basic versus applied research, and the role of corporate research. Since the mid-1980s, industrial research in the United States has been going through restructuring. Interviews with seventy-two scientists and eighteen managers working in six centralized corporate R&D laboratories in high-technology industry show that a new culture of dependence with a (...) mission-oriented approach is replacing the cherished culture of independence with a result-oriented approach. (shrink)