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  1. Representing Dispositions.Johannes Röhl & Ludger Jansen - 2011 - Journal of Biomedical Semantics 2 (4).
    Dispositions and tendencies feature significantly in the biomedical domain and therefore in representations of knowledge of that domain. They are not only important for specific applications like an infectious disease ontology, but also as part of a general strategy for modelling knowledge about molecular interactions. But the task of representing dispositions in some formal ontological systems is fraught with several problems, which are partly due to the fact that Description Logics can only deal well with binary relations. The paper will (...)
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  • Substance Concentrations as Conditions for the Realization of Dispositions.J. Hastings, L. Jansen, Stefan Schulz & C. Steinbeck - 2011 - In Ronald Cornet & Stefan Schulz (eds.), Semantic Applications in Life Sciences. Proceedings of the 4th International Workshop on Formal Biomedical Knowledge Representation, hosted by Bio-Ontologies 2010.
    Ontologies aim to represent what is general, by means of universal statements. In contrast, dispositional predications capture knowledge about what is likely to happen if a certain set of circumstances obtain, which is crucial in investigative research such as in drug discovery and systems biology, where entities which are constitutionally dissimilar can nevertheless have similar behavior in a biological context. While such dispositional properties are increasingly included in biomedical ontologies, the circumstances under which the dispositions are realized are seldom explicitly (...)
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  • Special Issue: Biomedical Ontology in Action.Olivier Bodenreider - 2009 - Applied Ontology 4 (1):1-4.
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  • Grains, Components and Mixtures in Biomedical Ontologies.Ludger Jansen & Schulz Stefan - 2011 - Journal of Biomedical Semantics 2 (4).
    BACKGROUND -/- In biomedical ontologies, mereological relations have always been subject to special interest due to their high relevance in structural descriptions of anatomical entities, cells, and biomolecules. This paper investigates two important subrelations of has_proper_part, viz. the relation has_grain, which relates a collective entity to its multiply occurring uniform parts (e.g., water molecules in a portion of water), and the relation has_component, which relates a compound to its constituents (e.g., molecules to the atoms they consist of). -/- METHOD -/- (...)
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