The discovery of the Higgs particle required a signal of 5σ significance. The rigid application of that condition is a convention that disregards more specific aspects of the given experiment. In particular, it does not account for the characteristics of the look elsewhere effect in the individual experimental context. The paper relates this aspect of data analysis to the question as to what extent theoretical reasoning should be admitted to play a role in the assessment of the significance of empirical (...) data. (shrink)

Increasing the “truth per dollar” of money spent on science is one legitimate long-run goal of the economics of science. But before this goal can be achieved, we need to increase our knowledge of the successes and failures of past and current reward structures of science. This essay reviews what economists have learned about the behavior of scientists and the reward structure of science. One important use of such knowledge will be to help policy-makers create a reward structure that is (...) more efficient in the future. (shrink)

Predictivism asserts that novel confirmations carry special probative weight. Epistemic pluralism asserts that the judgments of agents (about, e.g., the probabilities of theories) carry epistemic import. In this paper, I propose a new theory of predictivism that is tailored to pluralistic evaluators of theories. I replace the orthodox notion of use-novelty with a notion of endorsement-novelty, and argue that the intuition that predictivism is true has two roots. I provide a detailed Bayesian rendering of this theory and argue that pluralistic (...) theory evaluation pervades scientific practice. I compare my account of predictivism with those of Maher and Worrall. Introduction Why construction is a red herring for pluralist evaluators The unvirtuous accommodator Virtuous endorsers and the two roots of predictivism The two roots in Bayesian terms: the priors and background beliefs of endorsers Who are the pluralist evaluators? Two contemporary theories of predictivism 7.1 Maher: Reliable methods of theory construction 7.2 Worrall: The confirmation of core ideas Conclusion. (shrink)

Predictivism asserts that where evidence E confirms theory T, E provides stronger support for T when E is predicted on the basis of T and then confirmed than when E is known before T's construction and 'used', in some sense, in the construction of T. Among the most interesting attempts to argue that predictivism is a true thesis (under certain conditions) is that of Patrick Maher (1988, 1990, 1993). The purpose of this paper is to investigate the nature of predictivism (...) using Maher's analysis as a starting point. I briefly summarize Maher's primary argument and expand upon it; I explore related issues pertaining to the causal structure of empirical domains and the logic of discovery. (shrink)

Scientific hypotheses may either predict particular unknown facts or accommodate previously-known data. Although affirmed predictions are intuitively more rewarding than accommodations of established facts, opinions divide whether predictive hypotheses are also epistemically superior to accommodation hypotheses. This paper examines the contribution of predictive hypotheses to discoveries of several bio-molecular systems. Having all the necessary elements of the system known beforehand, an abstract predictive hypothesis of semiconservative mode of DNA replication was successfully affirmed. However, in defining the genetic code whose biochemical (...) basis was unclear, hypotheses were only partially effective and supplementary experimentation was required for its conclusive definition. Markedly, hypotheses were entirely inept in predicting workings of complex systems that included unknown elements. Thus, hypotheses did not predict the existence and function of mRNA, the multiple unidentified components of the protein biosynthesis machinery, or the manifold unknown constituents of the ubiquitin–proteasome system of protein breakdown. Consequently, because of their inability to envision unknown entities, predictive hypotheses did not contribute to the elucidation of cation theories remained the sole instrument to explain complex bio-molecular systems, the philosophical question of alleged advantage of predictive over accommodative hypotheses became inconsequential. (shrink)

The extra value of novel confirmation over accommodation is explained based on an analysis of the underdetermination of scientific theory building. Novel confirmation can provide information on the number of possible scientific alternatives to a predictively successful theory. This information, in turn, can raise the probability that the given theory is true or will be empirically viable in the future.