Rufus of Ephesus (fl.c.a.d.100) wrote a large body of works on a variety of medical topics. Generally speaking, the Arabic tradition is particularly important for the reconstruction of much of his œuvre. In the present article, I am going to present four new fragments of Rufus’On Melancholyand a fragment from an otherwise unknown monographOn Preferring Fresh Poppies. These new fragments provide fascinating new insights into Rufus’ approach to recording case histories.