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  1. Psychedelics: Recent Philosophical Discussions.Chris Letheby - 2017 - In Thomas Schramme & Steven Edwards (eds.), Handbook of the Philosophy of Medicine. Springer.
    “Classic”, serotonergic psychedelic drugs such as LSD and psilocybin are the objects of renewed attention in science and psychiatry. A recent spate of research has produced evidence that psychedelics might be safe and effective adjuncts to the treatment of mood and addictive disorders, agents of positive psychological change in healthy subjects, and valuable tools for studying the neural mechanisms of perception and cognition. This chapter surveys three philosophical debates that have arisen in response to this “renaissance” of psychedelic research. The (...)
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  • Psychedelics and environmental virtues.Nin Kirkham & Chris Letheby - 2022 - Philosophical Psychology 1:1-25.
    The urgent need for solutions to critical environmental challenges is well attested, but often environmental problems are understood as fundamentally collective action problems. However, to solve to these problems, there is also a need to change individual behavior. Hence, there is a pressing need to inculcate in individuals the environmental virtues — virtues of character that relate to our environmental place in the world. We propose a way of meeting this need, by the judicious, safe, and controlled administration of “classic” (...)
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  • Philosophy and classic psychedelics: A review of some emerging themes.Chris Letheby & Jaipreet Mattu - 2022 - Journal of Psychedelic Studies 5 (3):166-175.
    Serotonergic (or “classic”) psychedelics have struck many researchers as raising significant philosophical questions that, until recently, were largely unexplored by academic philosophers. This paper provides an overview of four emerging lines of research at the intersection of academic philosophy and psychedelic science that have gained considerable traction in the last decade: selfless consciousness, psychedelic epistemology, psychedelic ethics, and spiritual/religious naturalism. In this paper, we highlight philosophical questions concerning (i) psychedelics, self-consciousness, and phenomenal consciousness, (ii) the epistemic profile of the psychedelic (...)
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  • The Varieties of Psychedelic Epistemology.Chris Letheby - 2019 - In Nikki Wyrd, David Luke, Aimee Tollan, Cameron Adams & David King (eds.), Psychedelicacies: more food for thought from Breaking Convention. Strange Attractor Press.
    Recent scientific research suggests that altered states of consciousness induced by classic psychedelic drugs can cause durable psychological benefits in both healthy and patient populations. The phenomenon of ‘psychedelic transformation’ has many philosophically provocative aspects, not least of which is the claim commonly made by psychedelic subjects that their transformation is centrally due to some kind of learning or knowledge gain. Can psychedelic experiences really be a source of knowledge? From the vantage point of philosophical materialism or naturalism, a negative (...)
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  • Naturalizing psychedelic spirituality.Chris Letheby - 2017 - Zygon 52 (3):623-642.
    A pressing philosophical problem is how to respond to the existential, anxiety and disenchantment resulting from a naturalistic worldview that eschews transcendent foundations for meaning and value. This problem is becoming more urgent as the popularization of neuroscientific findings renders a disenchanted conception of human beings ever more vivid, compelling, and widespread. I argue that the study of transformative experiences occasioned by classic psychedelic drugs such as lysergic acid diethylamide and psilocybin may reveal the nature of a viable practical solution (...)
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  • How Do Psychedelics Reduce Fear of Death?Chris Letheby - 2024 - Neuroethics 17 (2):1-12.
    Increasing evidence suggests that psychedelic experiences, undergone in controlled conditions, can have various durable psychological benefits. One such benefit is reductions in fear of death, which have been attested in both psychiatric patients and healthy people. This paper addresses the question: how, exactly, do psychedelic experiences reduce fear of death? It argues, against some prominent proposals, that they do so mainly by promoting non-physicalist metaphysical beliefs. This conclusion has implications for two broader debates: one about the mechanisms of psychedelic therapy, (...)
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  • The epistemic innocence of psychedelic states.Chris Letheby - 2016 - Consciousness and Cognition 39:28-37.
    One recent development in epistemology, the philosophical study of knowledge, is the notion of ‘epistemic innocence’ introduced by Bortolotti and colleagues. This concept expresses the idea that certain suboptimal cognitive processes may nonetheless have epistemic (knowledge-related) benefits. The idea that delusion or confabulation may have psychological benefits is familiar enough. What is novel and interesting is the idea that such conditions may also yield significant and otherwise unavailable epistemic benefits. I apply the notion of epistemic innocence to research on the (...)
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  • Compassionate use of psychedelics.Martin Šurkala & Adam Greif - 2020 - Medicine, Health Care and Philosophy 23 (3):485-496.
    In the present paper, we discuss the ethics of compassionate psychedelic psychotherapy and argue that it can be morally permissible. When talking about psychedelics, we mean specifically two substances: psilocybin and MDMA. When administered under supportive conditions and in conjunction with psychotherapy, therapies assisted by these substances show promising results. However, given the publicly controversial nature of psychedelics, compassionate psychedelic psychotherapy calls for ethical justification. We thus review the safety and efficacy of psilocybin- and MDMA-assisted therapies and claim that it (...)
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  • Psilocybin, moralization and psychotherapy: a scoping review and a case report.Emiliano Loria, Elisabetta Lalumera & Ambra D’Imperio - forthcoming - Philosophical Psychology.
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  • Belief Now, True Belief Later: The epistemic advantage of self-related insights in psychedelic-assisted therapy.Chiara Caporuscio - 2022 - Philosophy and the Mind Sciences 3.
    Chris Letheby’s defence of psychedelic therapy hinges on the premise that psychedelic-facilitated insights about the self are in a better epistemic position than those about the external world. In this commentary, I argue that such a claim is not sufficiently defended. More precisely, I argue that one element is underexplored in Letheby’s otherwise compelling picture: namely, that unlike new beliefs about the external world, beliefs about oneself have the capacity to turn into self-fulfilling prophecies. Recognising the psychedelic experience and the (...)
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  • Primary states of consciousness: A review of historical and contemporary developments. [REVIEW]Felix Schoeller - 2023 - Consciousness and Cognition 113 (C):103536.
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