We argue for the existence of a moral dilemma– the ‘Puzzle of Lab-Grown Meat’– which challenges those who would endorse the moral permissibility of eating lab-grown meat, such as lab-grown chicken. The puzzle is that it is unclear why the moral permissibility of eating lab-grown meat should not extend to all lab-grown meat, such as white rhino or human, yet intuitively, we consider such meat morally impermissible to consume. To reject this challenge forces an endorsement of one of two implausibly (...) strong positions: either that all lab-grown meat is morally impermissible to eat or that all lab-grown meat is morally permissible to eat. To accept this challenge, is to attempt to solve the puzzle by providing a morally relevant distinction between ‘fair-game’ and ‘off-limits’ lab-grown meat. We consider a range of solutions but argue that each fails to solve the puzzle. (shrink)