The promises of nanotechnology have been framed by a variety of metaphors, that not only channel the attention of the public, orient the questions asked by researchers, and convey epistemic choices closely linked to ethical preferences. In particular, the image of the ‘therapeutic missile’ commonly used to present targeted drug delivery devices emphasizes precision, control, surveillance and efficiency. Such values are highly praised in the current context of crisis of pharmaceutical innovation where military metaphors foster a general mobilization of resources (...) from multiple fields of cutting-edge research. The missile metaphor, reminiscent of Paul Ehrlich’s ‘magic bullet’, has framed the problem in simple terms: how to deliver the right dose in the right place at the right moment? Chemists, physicists and engineers who design multi-functional devices operating in vitro can think in such terms, as long as the devices are not actually operating through the messy environment of the body. A close look at what has been done and what remains to be done suggests that the metaphor of the “therapeutic missile” is neither sufficient, nor even necessary. Recent developments in nanomedicine suggest that therapeutic efficacy cannot be obtained without negotiating with the biological milieu and taking advantage of what it affords. An ‘oikological’ approach seems more appropriate, more heuristic and more promising than the popular missile. It is based on the view of organism as an oikos that has to be carefully managed. The dispositions of nanocapsules have to be coupled with the affordances of the environment. As it requires dealing with nanoparticles as relational entities (defined by their potential for interactions) rather than as stable substances (defined by intrinsic properties) this metaphor eventually might well change research priorities in nanotechnology in general. (shrink)

lnek je zamen na vybran implikace mezi sociologickou hermeneutikou (pstup) a analzou metafor (analytick koncept). Konkrtn je een vztah lingvistickho kontextu textu (jako empirickho korpusu) a vyplvajcch (skrytch) implikac, kter jsou odhaliteln dky kontextu metaforickho vznamu. Uren vztah me pomoci k zpesnn role sociologick hermeneutiky v socilnch vdch, konkrtn k monosti volby v kvalitativnch metodch skrze kritickou metodologii. Vstupem lnku je konstatovn siln vazby mezi tvorbou kontextulnch metafor a postavenm polysmickho slova ve vt, kter dky tomu tvo zkladnm referenn objekt (...) empirickho korpusu pro samotnou analzu. (shrink)

The emergence of new technologies regularly involves comparisons with previous innovations. For instance, analogies with asbestos and genetically modified organisms have played a crucial role in the early societal debate about nanotechnology. This article explores the power of analogies in such debates and how they could be effectively and responsibly employed for imagining and governing emerging technologies in general and nanotechnology in particular. First, the concept of analogical imagination is developed to capture the explorative and anticipatory potential of analogies. Yet (...) analogies do not simply stimulate imagination, they also restrict it by framing emerging technologies in specific ways. Thus, second, the article argues that tracing the rhetorical and persuasive power of analogical arguments is essential for understanding how analogies are constructed to legitimise assessments, funding policies, and governance approaches. Third, the article addresses factors that account for the persuasiveness of analogies in debates about emerging technologies. The article concludes with reflections on how analogical imagination and an enhanced analogical sensibility for framing and persuasive effects can foster responsible research and innovation. (shrink)

Changing images of work in discourse both portray and co-constitute the shift from an industrial to a postindustrial economy. Specifically, work metaphors appear in extra-scientific and intra-scientific discourse on workers and work structures in the natural and social world. An analysis of the entomological discourse from the late nineteenth century to the present shows changes in these metaphors that overlap with the discourse of change in human work and organizational structures. For instance, the metaphor of a busy bee within an (...) efficient hive had traditionally evoked a comparison to the modern industrial workplace. The discourse on the hive currently more closely resembles a postindustrial conception of work. Discourse analysis can illustrate the role of language in co-constructing shared changes in image of work. (shrink)

The article traces the origin and development of the concept of social skills in first and foremost American academic discourse. As soon as the concept of social skills was coined, the concern for people lacking such skills started and has been on the increase ever since. After the analysis of the academic history of the concept follows an examination of the implementation of a range of assessment instruments and training programmes related to social skills in contemporary Danish welfare institutions. The (...) analysis forwarded in the article thus demonstrates how an intellectual idea may develop and travel - and on its journey connect to pre-existing cultural logics and societal concerns. The idea of social skills has through its development been made uncontroversial – everybody wants to be skilful. The concept does, however, convey an individualistic view on social life and imposes a reflexivity over own performance on the participants. Further, its normative character contributes to a problematization of those who are perceived to lack these skills. (shrink)

Editor's Comment: One of the functions of the journal is to develop an awareness of its own history. These papers are online-only papers that discuss the first ten years of the journal going back to 1969. Every so often the journal publishes synoptic articles that take a broad approach to the beginning of the Society and the journal to treat major themes and topics. As one can clearly see EPAT published many of the luminaries that helped to shape the discipline.

This article compares two different bodies of theories concerning the role of the genome in life processes. The first group of theories can be indicated as referring to the gene-centric paradigm. Dominated by an informational myth and a mechanistic Cartesian body/mind and form/substance dualism, this considers the genome as an ensemble of discrete units of information governing human body and behavior, and remains hegemonic in life sciences and in the public imagination. The second body of theories employs the principle of (...) the extraordinary plasticity of the (body-)organism and emphasizes the value of the (body-)organism-environment mutual interchange, known as ‘the epigenetic approach’. This approach is outlined, showing a gradual, paradigmatic shift from the genecentric towards an epigenetic approach can be observed in the ‘scientific landscape’ over the last 20 years. The article concludes by formulating the argument that this ‘epigenetic turn’ in life sciences has some important implication for renewing epistemological basis of social sciences. (shrink)

The relation between theoretical models and metaphors has been studied since at least the 1950s. The relation between metaphors and mathematical modelling is less well researched. This article takes the media coverage of the foot and mouth modelling exercise in 2001 as an occasion to examine the metaphors of mathematical modelling that were proposed by the UK press during that time to make sense of this new scientific policy tool. One can detect a gradual change in metaphor use by the (...) newspapers from conceptualizing modellers as detectives and models as mapping tools to modellers as soldiers and heroes, to modellers as liars and models as tools to distort the truth. This seems to indicate a shift in reporting from seeing models as a legitimate and "objective" basis used by decision makers to pursue science-based policies towards seeing models as tools used to legitimize increasingly difficult political decisions. (shrink)

Metaphors are not just decorative rhetorical devices that make speech pretty. They are fundamental tools for thinking about the world and acting on the world. The language we use to make a better world matters; words matter; metaphors matter. Words have consequences - ethical, social and legal ones, as well as political and economic ones. They need to be used ‘responsibly’. They also need to be studied carefully – this is what we want to do through this editorial and the (...) related thematic collection. In the context of synthetic biology, natural and social scientists have become increasingly interested in metaphors, a wave of interest that we want to exploit and amplify. We want to build on emerging articles and books on synthetic biology, metaphors of life and the ethical and moral implications of such metaphors. This editorial provides a brief introduction to synthetic biology and responsible innovation, as well as a comprehensive review of literature on the social, cultural and ethical impacts of metaphor use in genomics and synthetic biology. Our aim is to stimulate an interdisciplinary and international discussion on the impact that metaphors can have on science, policy and publics in the context of synthetic biology. (shrink)

Drawing from contemporary social science studies on the shifting regime of research governance, this paper extends the literature by utilizing a metaphoric image—research is a game—observed in a field engagement with 82 American, British, and Danish crop and plant scientists. It theorizes respondents’ thinking and practices by placing the rules of the research game in dynamic and interactive tension between the scientific, social, and political-economic contingencies that generate opportunities or setbacks. Scientists who play the game exploit opportunities and surmount setbacks (...) by adopting strategies and reinventing tactics in order to maximize their winnings and to minimize their losses. Winners become superstars who decree what is open, closed, or doable science for the majority of the scientific community. (shrink)

Excellence and frontier research have made inroads into European research policymaking and structure political agendas, funding programs and evaluation practices. The two concepts travelled a long way from the United States and have derived from contexts outside of science. Following their conceptual journey, we ask how excellence and frontier research have percolated into European science and higher education policies and how they have turned into lubricants of competition that buttress an ongoing reform process in Europe.

Synthetic biology represents a relatively young field of research which has developed into an important scientific endeavour. Characterised by a high degree of interdisciplinary work crossing disciplinary boundaries, such as biology, mathematics and engineering, SynBio has been, since its beginning, devoted to creating new biological functions, metabolic pathways or even minimal organisms. Although its often-articulated aim of developing new forms of life has so far not been archived, SynBio nowadays represents a well-established biotechnological approach and it has also attracted public (...) concern, especially since Craig Venter’s work on Mycoplasma Mycoides JCVI-syn1.0. Taking these developments as a starting point, the paper empirically investigates the metaphorical representations of SynBio in two leading German media publications, the daily newspaper Die Frankfurter Allgemeine Zeitung and the weekly magazine Der Spiegel between 2000 and 2010. Using a novel combination of metaphor and co-occurrence analysis, the paper engages in a systematic examination of implicit moral implications inherent in linguistic images permeating this news coverage. It demonstrates a method of how media-metaphorical representations and their moral implications of SynBio could analytically be revealed and analysed. In doing so, it aims at contributing to empirical ethical analyses of the news coverage on SynBio in particular and offers an approach that methodologically adds to literature on responsible language use, which is emerging in science and technology studies and ethical analyses of new technologies. (shrink)

In the general understanding, and also in scientific practice, technology and society are viewed as two distinct entities. Related to this view is the assumption that technology and human experience are quite different and unconnected and also the idea that modernity has uprooted, de-contextualized and disembodied technical rationality. Taking a contrary approach, this study represents a theoretical exploration aimed at showing that in the domain of technological development, there are significant margins for maneuver in which to recuperate and valorize human (...) and social action. As a work of theoretical sociology or social epistemology, this thesis approaches its subject from the theoretical background of the philosophy and sociology of technique. The historical and conventional assumptions of this theoretical background, it is argued, have been and continue to be characterized by a hegemonically defined essentialist paradigm. This paradigm has been fiercely counteracted by two opposed approaches, critical theory and pragmatism. The present work combines these approaches, usually considered mutually incompatible, for the development of a new theoretical gaze or perspective. The aim has been to engage in a theoretical research oriented to a new philosophy of praxis in order to instigate a critical and constructivist approach to technology. The main result expected of this work is the provision of a problematized and multifaceted semantic map leading to a multidimensional conceptual re-integration of skilled experience in human technical action. (shrink)

In this talk I present the main results from Anta (2021), namely, that the theoretical division between Boltzmannian and Gibbsian statistical mechanics should be understood as a separation in the epistemic capabilities of this physical discipline. In particular, while from the Boltzmannian framework one can generate powerful explanations of thermal processes by appealing to their microdynamics, from the Gibbsian framework one can predict observable values in a computationally effective way. Finally, I argue that this statistical mechanical schism contradicts the Hempelian (...) (1958) thesis that the predictive power of a scientific theory is directly proportional to its explanatory potential, and vice versa. (shrink)

We develop a new metaphor account where metaphors become surrogate variables for different but related phenomena. As we will argue, subrogation is the result of the interplay between the things inspired by the metaphor and the empirical dynamics that result from such inspiration. In particular, we focus on adaptive radiation, a major concept of evolutionary biology. Our study suggests that there is no distinct phenomenon, process, or pattern in nature than can be identified as adaptive radiation. What we have instead (...) is a grouping variable that has surrogated different evolutionary phenomena into one expansive label. We believe this analysis of metaphors helps better understand the value of metaphors for science not only as a provider of epistemic and cognitive virtues but most importantly, as a crucial research tool that can both help and divert scientific experimentation. (shrink)