Philosophers have usually offered a number of ways of describing hypotheses generation, but all aim at demonstrating that the activity of generating hypotheses is paradoxical, illusory or obscure, and then not analysable. Those descriptions are often so far from Peircian pragmatic prescription and so abstract to result completely unknowable and obscure. The “computational turn” gives us a new way to understand creative processes in a strictly pragmatic sense. In fact, by exploiting artificial intelligence and cognitive science tools, computational philosophy allows (...) us to test concepts and ideas previously conceived only in abstract terms. It is in the perspective of these actual computational models that I find the central role of abduction in the explanation of creative reasoning in science. Creativity and discovery are no more seen as a mysterious irrational process, but, thanks to constructive accounts, as a complex relationship among different inferential steps that can be clearly analysed and identified. I maintain that the computational philosophy analysis of model-based and manipulative abduction and of external and epistemic mediators is important not only to delineate the actual practice of abduction, but also to further enhance the development of programs computationally adequate in rediscovering, or discovering for the first time, for example, scientific hypotheses or mathematical theorems. (shrink)