In recent years, the ontological similarities between the foundations of quantum mechanics and the emptiness teachings in Madhyamika–Prasangika Buddhism of the Tibetan lineage have attracted some attention. After briefly reviewing this unlikely connection, I examine ideas encountered in condensed-matter physics that resonate with this view on emptiness. Focusing on the particle concept and emergence in condensed-matter physics, I highlight a qualitative correspondence to the major analytical approaches to emptiness.