The molecule, as a perfect and ageless building block of matter that exists beyond human reach, has been an object of fascination and admiration since the 19th century. However, the discourse surrounding nanotechnology – at least at its most optimistic – promises the possibility of human mastery over this domain and, as a result, over all matter. This belief carries forward the old idea of a division between a realm of the base, material and particular, on one hand, and a (...) realm of the perfect, immaterial and abstract, on the other, one which today is most powerfully expressed in information discourse. Within this framework, nanotechnology promises the ability to negotiate and even dissolve this division, allowing matter itself to be treated as a kind of information. The most enthusiastic adherents of this idea believe that this will one day allow us to ‘reprogram’ material reality itself. (shrink)