The objective of this article is to conceptualize and evaluate the transhumanist movement by applying a Nietzschean critique to its techno-progressive agenda of human enhancement. The investigation itself is divided into three distinctive, yet methodologically intertwined steps: first, I will present an exegetical approach by circumscribing the discussion concerning the alleged similarities and disparities between the transhumanist notion of transforming the human into a posthuman being and Nietzsche’s concept of education, understood as self-overcoming; secondly, in a more practical and future-oriented (...) manner, I will consider some of the major aporias for conceptualizing a ‘Nietzschean transhumanism’ by confronting the techno-progressive idea of morphological freedom with Nietzsche’s critical approach to the commerce- and consumer-oriented mentality of the non-creative modern individual; finally, I will employ Nietzsche’s complex treatment of nihilism in order to formulate a critical evaluation of transhumanism’s cultural implications. My fundamental conclusion will be that the techno-progressive agenda does not strive to overcome human limitations by coping with the tragic nature of life in a Nietzschean sense, but merely promotes the nihilistic dream of Zarathustra’s ‘last human’ to establish a common happiness by eradicating the Dionysian reality of all existence. (shrink)