In 1875 T. H. Huxley discovered that a secretion from the mouldpenicillium glaucumhad an ability, unconnected with oxygen deprivation, to inhibit bacterial growth. He recorded his observations in his notebooks and in a single letter to John Tyndall, who at that time was a friend of Lister and a correspondent of Pasteur. Neither Huxley nor Tyndall looked for an explanation of this phenomenon, and neither told anyone else about it.

This paper argues that the 1953 double-helix solution to the problem of DNA structure was understood, at the time, as a blow within a fiercely fought dispute over the material nature of life. The paper examines the debates, between those for whom life was a purely material phenomenon and religious people for whom it had a spiritual significance, that were waged from the aftermath of the First World War to the 1960s. It looks at the developing arguments of early promoters (...) of molecular biology, including J.D. Bernal, his pupil Max Perutz and his pupil Francis Crick, on the one side, and of the so-called ‘Inkling’ cluster of writers including C.S. Lewis and J.R.R. Tolkien, on the other. This debate was conducted through polemical works, journalism, and science fiction and through the Festival of Britain and can be followed through the commentary of Jacob Bronowski. The paper concludes with the model of the double helix now at the Science Museum, which can be considered an archaeological relic of a battle in a war which is still being fought. (shrink)