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  1. Rewriting the genetic bond: Gene editing and our understanding of genetic parenthood.Shelly Simana & Vardit Ravitsky - 2022 - Bioethics 37 (3):265-274.
    One of the most prominent justifications for the use of germline gene editing (GGE) is that it would allow parents to have a “genetically related child” while preventing the transmission of genetic disorders. However, we argue that since future uses of GGE may involve large-scale genetic modifications, they may affect the genetic relatedness between parents and offspring in a meaningful way: Due to certain genetic modifications, children may inherit much less than 50% of their DNA from each parent. We show (...)
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  • The use of human artificial gametes and the limits of reproductive freedom.Dustin Gooßens - 2020 - Bioethics 35 (1):72-78.
    ABSTRACT Recent developments in generating gametes via in vitro gametogenesis (IVG) from induced pluripotent stem cells (iPSCs) and their successful use for reproductive purposes in animals strongly suggest that soon these methods could also be used in human reproduction. At least two questions emerge in this context: (a) if a legislator should permit their use and (b) if ethical claims emerge that support their provision, e.g., by public health care systems. This urges an ethical reflection of the new reproductive options (...)
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