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  1. Are There Moral Differences Between Maternal Spindle Transfer and Pronuclear Transfer?César Palacios-González - 2017 - Medicine, Health Care and Philosophy 20 (4):503-511.
    This paper examines whether there are moral differences between the mitochondrial replacement techniques that have been recently developed in order to help women afflicted by mitochondrial DNA diseases to have genetically related children absent such conditions: maternal spindle transfer and pronuclear transfer. Firstly, it examines whether there is a moral difference between MST and PNT in terms of the divide between somatic interventions and germline interventions. Secondly, it considers whether PNT and MST are morally distinct under a therapy/creation optic. Finally, (...)
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  • ‘Yes’ to Mitochondrial Replacement Techniques and Lesbian Motherhood: A Reply to Françoise Baylis.César Palacios-González & Giulia Cavaliere - 2019 - Journal of Medical Ethics 45 (4):280-281.
    In a recent paper – Lesbian motherhood and mitochondrial replacement techniques: reproductive freedom and genetic kinship – we argued that lesbian couples who wish to have children who are genetically related to both of them should be allowed access to mitochondrial replacement techniques. Françoise Baylis wrote a reply to our paper –‘No’ to lesbian motherhood using human nuclear genome transfer– where she challenges our arguments on the use of MRTs by lesbian couples, and on MRTs more generally. In this reply (...)
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  • Resource Allocation, Treatment, Disclosure, and Mitochondrial Replacement Techniques.César Palacios-gonzález - 2017 - Cambridge Quarterly of Healthcare Ethics 26 (2):278-287.
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  • Lesbian Motherhood and Mitochondrial Replacement Techniques: Reproductive Freedom and Genetic Kinship.Giulia Cavaliere & César Palacios-González - 2018 - Journal of Medical Ethics 44 (12):835-842.
    In this paper, we argue that lesbian couples who wish to have children who are genetically related to both of them should be allowed access to mitochondrial replacement techniques. First, we provide a brief explanation of mitochondrial diseases and MRTs. We then present the reasons why MRTs are not, by nature, therapeutic. The upshot of the view that MRTs are non-therapeutic techniques is that their therapeutic potential cannot be invoked for restricting their use only to those cases where a mitochondrial (...)
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  • Does Egg Donation for Mitochondrial Replacement Techniques Generate Parental Responsibilities?César Palacios-González - 2018 - Journal of Medical Ethics 44 (12):817-822.
    Children created through mitochondrial replacement techniques are commonly presented as possessing 50% of their mother’s nuclear DNA, 50% of their father’s nuclear DNA and the mitochondrial DNA of an egg donor. This lab-engineered genetic composition has prompted two questions: Do children who are the product of an MRT procedure have three genetic parents? And, do MRT egg donors have parental responsibilities for the children created? In this paper, I address the second question and in doing so I also address the (...)
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