A formal theory of oppositions and opposites is proposed on the basis of a non- Fregean semantics, where opposites are negation-forming operators that shed some new light on the connection between opposition and negation. The paper proceeds as follows. After recalling the historical background, oppositions and opposites are compared from a mathematical perspective: the first occurs as a relation, the second as a function. Then the main point of the paper appears with a calculus of oppositions, by means of a (...) non-Fregean semantics that redefines the logical values of various sorts of sentences. A num- ber of topics are then addressed in the light of this algebraic semantics, namely: how to construct value-functional operators for any logical opposition, beyond the classical case of contradiction; Blanché's "closure problem", i.e., how to find a complete structure connecting the sixteen binary sentences with one another. All of this is meant to devise an abstract theory of opposition: it encompasses the relation of consequence as subalternation, while relying upon the use of a primary "proto- negation" that turns any relatum into an opposite. This results in sentential negations that proceed as intensional operators, while negation is broadly viewed as a difference-forming operator without special constraints on it. (shrink)