In this paper non-Hausdorff manifolds as potential basic objects of General Relativity are investigated. One can distinguish four stages of identifying an appropriate mathematical structure to describe physical systems: kinematic, dynamical, physical reasonability, and empirical. The thesis of this paper is that in the context of General Relativity, non-Hausdorff manifolds pass the first two stages, as they enable one to define the basic notions of differential geometry needed to pose the problem of the evolution-distribution of matter and are not in (...) conflict with the Einstein equations. With regard to the third stage, various potential conflicts with physical reasonability conditions are considered with a tentative conclusion that non-Hausdorff manifolds are more likely to pass this stage than is typically assumed. When dealing with some of these problems, the modal interpretation of non-Hausdorff manifolds is invoked, according to which they represent bundles of alternative possible spacetimes rather than single spacetimes. (shrink)