A model of the neuropsychology of anxiety is proposed. The model is based in the first instance upon an analysis of the behavioural effects of the antianxiety drugs in animals. From such psychopharmacologi-cal experiments the concept of a “behavioural inhibition system” has been developed. This system responds to novel stimuli or to those associated with punishment or nonreward by inhibiting ongoing behaviour and increasing arousal and attention to the environment. It is activity in the BIS that constitutes anxiety and that (...) is reduced by antianxiety drugs. The effects of the antianxiety drugs in the brain also suggest hypotheses concerning the neural substrate of anxiety. Although the benzodiazepines and barbiturates facilitate the effects of γ-aminobutyrate, this is insufficient to explain their highly specific behavioural effects. Because of similarities between the behavioural effects of certain lesions and those of the antianxiety drugs, it is proposed that these drugs reduce anxiety by impairing the functioning of a widespread neural system including the septo-hippocampal system, the Papez circuit, the prefrontal cortex, and ascending monoaminergic and cholinergic pathways which innervate these forebrain structures. Analysis of the functions of this system suggests that it acts as a comparator: it compares predicted to actual sensory events and activates the outputs of the BIS when there is a mismatch or when the predicted event is aversive. Suggestions are made as to the functions of particular pathways within this overall brain system. The resulting theory is applied to the symptoms and treatment of anxiety in man, its relations to depression, and the personality of individuals who are susceptible to anxiety or depression. (shrink)

To understand the endogenous components of the event-related brain potential (ERP), we must use data about the components' antecedent conditions to form hypotheses about the information-processing function of the underlying brain activity. These hypotheses, in turn, generate testable predictions about the consequences of the component. We review the application of this approach to the analysis of the P300 component. The amplitude of the P300 is controlled multiplicatively by the subjective probability and the task relevance of the eliciting events, whereas its (...) latency depends on the duration of stimulus evaluation. These and other factors suggest that the P300 is a manifestation of activity occurring whenever one's model of the environment must be revised. Tests of three predictions based on this “context updating” model are reviewed. Verleger's critique is based on a misconstrual of the model as well as a partial and misleading reading of the relevant literature. (shrink)

Images of mindis an exciting book, well-written and wellorganized, but many of the connections the authors draw between PET scan results and more general psychological issues are somewhat strained.

This book delivers much more than its title appears to promise; it is not merely a description of current methods for remotely monitoring brain activity. It primarily concentrates on just one such method: positron emission tomography, but it demonstrates beautifully how far that technique can now take us in the quest to discover the mechanisms underlying thought.

A methodological problem may distort the implications derived from the metabolism scans of the brain, but Posner & Raichle may have found neural networks which underlie the analytical and synthetical hemispheric data processing mechanism. This methodological problem is that a large regional consumption of energy, detected by the PET technique, is not necessarily related to more data processing. It may be related to the inefficiency of the neural system at this region.

The approach adopted by Posner & Raichle in this book, with its strong emphasis on the cognitive level of description, is ideally suited to the study of psychotic illnesses. However, their discussion of depression and schizophrenia is based on a very small number of studies and involves ad hoc arguments derived largely from neuroanatomy. Their conclusions are almost certainly wrong.

This volume explores how functional brain imaging techniques like positron emission tomography have influenced cognitive studies. The first chapter outlines efforts to relate human thought and cognition in terms of great books from the late 1800s through the present. Chapter 2 describes mental operations as they are measured in cognitive science studies. It develops a framework for relating mental operations to activity in nerve cells. In Chapter 3, the PET method is reviewed and studies are presented that use PET to (...) map the striate cortex and to activate extrastriate motion, color, and form areas. Chapter 4 shows how top down processes involving attention can lead to activation of these same areas in the detection of targets, visual search, and visual imagery. This chapter reveals complex networks of activations. Chapters 5 and 6 deal with the presentation of words. Chapter 5 illustrates PET studies of the anatomy of visual word processing and shows how the circuitry used for generating novel uses of words changes as the task becomes automated. Chapter 6 applies high density electrical recording to explore these activations in real time and to show how a constant anatomy can be reprogrammed by task instructions to produce and perform different cognitive tasks. Chapter 7 shows how studies of brain lesions and PET converge on common networks underlying attentional functions such as visual orienting, target detection, and maintenance of the alert state. Chapters 8 and 9 apply the network approach to examine normal development of attention in infants and pathological conditions resulting from brain damage, and psychiatric pathologies of depression, schizophrenia, and attention deficit disorder. In Chapter 10, new developments such as functional MRI are discussed in terms of future developments and integration of cognitive neuroscience. (shrink)

This is an excellent book but it lacks a detailed presentation and formulation of images of memory. Positron emission tomography (PET) findings sometimes raise more enigmatic questions than they answer, with differences between studies and differences with established lesion evidence. Perhaps the book could have been more critical in its analysis of these enigmas, covering more of the basic issues and assumptions underlying PET research.

PET studies in domains like vision and attention have been successful because the experiments are the product of highly articulated theories. In contrast, the results of PET studies investigating language processing are difficult to interpret. We suggest that this difficulty is due to the more tentative connection of these experiments with the insights of psycholinguistics and linguistic theory.

The authors ofImages of mindhave been highly successful in unravelling the neural basis of complex brain functions. Their emphasis on top-down processingin experimental neuroscience is especially important and, it is hoped, influential. Tracking brain activation accurately botli in space and in time would benefit from studiesofindividual subjects without relying on grand average data.

Posner & Raichle illustrate how neuroimaging blends profitably with neuropsychology and electrophysiology to advance cognitive theory. Recognizing that there are limitations to each of these techniques, we nonetheless argue that their confluence has fundamentally changed the way cognitive psychologists think about problems of the mind.

Abstract: Each affective state has distinct motor-expressions, sensory perceptions, autonomic, and cognitive patterns. Panksepp (1998) proposed seven neural affective systems of which the SEEKING system, a generalized approach-seeking system, motivates organisms to pursue resources needed for survival. When an organism is presented with a novel stimulus, the dopamine (DA) in the nucleus accumbens septi (NAS) is released. The DA circuit outlines the generalized mesolimbic dopamine-centered SEEKING system and is especially responsive when there is an element of unpredictability in forthcoming rewards. (...) We propose that when the outcome of this interaction is unexpected or unanticipated then Panksepp’s “cognitive or expectancy reset” mechanism involving the cognitive dissonance would yield the subjective emotion of surprise. In order to appropriately react to the environment’s stimuli one needs fundamental processes that would enable one to distinguish between what is novel and what has been already experienced, as well as the different degrees of novelty. Novel events are those whose essential features of the representation (visceral and perceptual) are altered and being discrepant provoke more sustained attention. Novelty arises from salient and arousing events and the organism experiences surprise, as coming out of a habitual state. In this framework, we shall look at established theories of emotions and propose a different approach to their taxonomy. (shrink)

Extraversion has two central characteristics: (1) interpersonalengagement, which consists of affiliation (enjoying and valuing close interpersonal bonds, being warm and affectionate) and agency (being socially dominant, enjoying leadership roles, being assertive, being exhibitionistic, and having a sense of potency in accomplishing goals) and (2) impulsivity, which emerges from the interaction of extraversion and a second, independent trait (constraint). Agency is a more general motivational disposition that includes dominance, ambition, mastery, efficacy, and achievement. Positive affect (a combination of positive feelings and (...) motivation) is closely associated with extraversion. Extraversion is accordingly based on positiveincentivemotivation. (shrink)

This is a 2020 revision of my 1988 dissertation "The Choreography of the Soul" with a new Foreword, a new Conclusion, a substantially revised Preface and Introduction, and many improvements to the body of the work. However, the thesis remains the same. A theory of consciousness and trance states--including psychedelic experience--is developed. Consciousness can be analyzed into two distinct but generally interrelated systems, which I call System X and System Y. System X is the emotional-visceral-kinaesthetic body. System X is a (...) harmonic system of "endokinetic" (internal bodily) and "ectokinetic" (emotionally expressive) movement. System Y is a "teleokinetic" (goal directed) system that includes language, cognition, perception, voluntary motor control, manipulation of the environment, etc. Contrary to theories of consciousness prevalent in the Western philosophical traditions that begin with Plato, I argue that System Y is secondary to and dependent upon System X, not the reverse. In building my thesis I draw upon the work of Friedrich Nietzsche, psychoanalysis, Jungian depth psychology, political anthropology, modern neuroscience, Pythagorean music theory, and the mathematical theory of harmonic systems. (shrink)

Despite the fact that attention is a core property of all perceptual and cognitive operations, our understanding of its neurophysiological mechanisms is far from complete. There are many theoretical models that try to fill this gap in knowledge, though practically all of them concentrate only on either involuntary (bottom-up) or voluntarily (top-down) aspect of attention. At the same time, both aspects of attention are rather integrated in the living brain. In this chapter we attempt to conceptualise both aspects of attentional (...) state within the theory of Operational Architectonics of brain and mind functioning, which provides a plausible theoretical basis for neurophysiological understanding of how attention is brought to existence in the living brain. (shrink)

To understand the endogenous components of the event-related brain potential (ERP), we must use data about the components' antecedent conditions to form hypotheses about the information-processing function of the underlying brain activity. These hypotheses, in turn, generate testable predictions about the consequences of the component. We review the application of this approach to the analysis of the P300 component. The amplitude of the P300 is controlled multiplicatively by the subjective probability and the task relevance of the eliciting events, whereas its (...) latency depends on the duration of stimulus evaluation. These and other factors suggest that the P300 is a manifestation of activity occurring whenever one's model of the environment must be revised. Tests of three predictions based on this “context updating” model are reviewed. Verleger's critique is based on a misconstrual of the model as well as a partial and misleading reading of the relevant literature. (shrink)