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  1. Justifying an Intentional Species Extinction: The Case of Anopheles Gambiae.Daniel Edward Callies & Yasha Rohwer - 2022 - Environmental Values 31 (2):193-210.
    Each year, over 200 million people are infected with the malaria parasite, nearly half a million of whom succumb to the disease. Emerging genetic technologies could, in theory, eliminate the burden of malaria throughout the world by intentionally eradicating the mosquitoes that transmit the disease. In this paper, we offer an ethical examination of the intentional eradication of Anopheles gambiae, the main malaria vector of sub-Saharan Africa. In our evaluation, we focus on two main considerations: the benefit of alleviating the (...)
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  • An Ethical Overview of the CRISPR-Based Elimination of Anopheles gambiae to Combat Malaria.India Jane Wise & Pascal Borry - forthcoming - Journal of Bioethical Inquiry:1-10.
    Approximately a quarter of a billion people around the world suffer from malaria each year. Most cases are located in sub-Saharan Africa where Anopheles gambiae mosquitoes are the principal vectors of this public health problem. With the use of CRISPR-based gene drives, the population of mosquitoes can be modified, eventually causing their extinction. First, we discuss the moral status of the organism and argue that using genetically modified mosquitoes to combat malaria should not be abandoned based on some moral value (...)
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  • Teilhard de Chardin’s Oeuvre Within an Ongoing Discussion of a Gene Drive Release for Public Health Reasons.Anto Čartolovni - 2017 - Life Sciences, Society and Policy 13 (1):1-15.
    Within the domain of public health, vector-borne diseases are among the most vehemently discussed issues. Recent scientific breakthroughs in genome editing technology provided a solution to this issue in the form of a gene drive that might decrease and even eradicate vector-borne diseases. Gene drives are engineered, and designed genes that can break typical inheritance rules and be passed to almost all of the carrier’s offspring. This genome editing and gene drive technology has become a powerful tool for ecological and (...)
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  • Experts’ Moral Views on Gene Drive Technologies: A Qualitative Interview Study.Annelien L. Bredenoord, Karin R. Jongsma & N. de Graeff - 2021 - BMC Medical Ethics 22 (1):1-15.
    BackgroundGene drive technologies promote the rapid spread of a particular genetic element within a population of non-human organisms. Potential applications of GDTs include the control of insect vectors, invasive species and agricultural pests. Whether, and if so, under what conditions, GDTs should be deployed is hotly debated. Although broad stances in this debate have been described, the convictions that inform the moral views of the experts shaping these technologies and related policies have not been examined in depth in the academic (...)
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  • Better Humans and Evolutionary Nudge.Ann Boyd - 2017 - Eubios Journal of Asian and International Bioethics 27 (4):116-120.
    Gene therapy especially newly developed CRISPR gene editing spawns complex conversations, ethically, emotionally, politically, and economically, within and among countries. As new technology makes its way through the experimental development, assessment, refinement and application, it is not too soon to begin the policy and ethical dialogues about how and when and for what purpose it is used. Certainly experiments should continue to assess whether CRISPR is the long sought for means to effective gene therapy. It will probably be used in (...)
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