BackgroundResearch with cerebral organoids is beginning to make significant progress in understanding the etiology of autism spectrum disorder (ASD). Brain organoid models can be grown from the cells of donors with ASD. Researchers can explore the genetic, developmental, and other factors that may give rise to the varieties of autism. Researchers could study all of these factors together with brain organoids grown from cells originating from ASD individuals. This makes brain organoids unique from other forms of ASD research. They are (...) like a multi-tool, one with significant versatility for the scope of ASD research and clinical applications. There is hope that brain organoids could one day be used for precision medicine, like developing tailored ASD drug treatments.Main bodyBrain organoid researchers often incorporate the medical model of disability when researching the origins of ASD, especially when the research has the specific aim of potentially finding tailored clinical treatments for ASD individuals. The neurodiversity movement—a developmental disability movement and paradigm that understands autism as a form of natural human diversity—will potentially disagree with approaches or aims of cerebral organoid research on ASD. Neurodiversity advocates incorporate a social model of disability into their movement, which focuses more on the social, attitudinal, and environmental barriers rather than biophysical or psychological deficits. Therefore, a potential conflict may arise between these perspectives on how to proceed with cerebral organoid research regarding neurodevelopmental conditions, especially ASD.ConclusionsHere, we present these perspectives and give at least three initial recommendations to achieve a more holistic and inclusive approach to cerebral organoid research on ASD. These three initial starting points can build bridges between researchers and the neurodiversity movement. First, neurodiverse individuals should be included as co-creators in both the scientific process and research communication. Second, clinicians and neurodiverse communities should have open and respectful communication. Finally, we suggest a continual reconceptualization of illness, impairment, disability, behavior, and person. (shrink)

This article aims to address the importance of Black Theology of Liberation mainly focussing on the unheard cry of people living with disabilities. Black Theology in its origin is linked to communities of black oppressed beings; its task is to seriously consider the experiences and situation of those who reside in the zone of non-being. In this article, people living with disabilities represent those who reside underside modernity and history, which simply entails that people living with disabilities lack the quality (...) of being recognised as human beings, but as sub-humans who are lifeless. Some scholars of Black Theology eloquently wrestles with the lifelessness fruit which the empire continues to bear by arguing that the Black Theology of Liberation is a theology that aims to give life to victims of lifelessness. It is argued that people living with disabilities in black communities experience a lack of accessibility to transportation, the health sector, education, and building infrastructures in South Africa. The lack of accessibility to opportunities and resources for people living with disabilities portrays a denial of human rights and equality; it instead, promotes the state of lifelessness to people living with disabilities. Contribution: The article adopts ‘The Cry for Life’ declaration which stresses the affirmation of life to all human beings despite their disabilities. The cry for impilo [life] by people living with disabilities is what makes Black Theology an epistemological tool that is derived from below in the search for impilo. (shrink)