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  1. Studies on Molecular Mechanisms of Prebiotic Systems.Walter Riofrio - 2012 - Foundations of Science 17 (3):277-289.
    Lately there has been a growing interest in evolutionary studies concerning how the regularities and patterns found in the living cell could have emerged spontaneously by way of self-assembly and self-organization. It is reasonable to postulate that the chemical compounds found in the primitive Earth would have mostly been very simple in nature, and would have been immersed in the natural dynamics of the physical world, some of which would have involved self-organization. It seems likely that some molecular processes self-organized (...)
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  • Receptor Oligomerization as a Process Modulating Cellular Semiotics.Franco Giorgi, Luis Emilio Bruni & Roberto Maggio - 2010 - Biosemiotics 3 (2):157-176.
    The majority of G protein-coupled receptors (GPCRs) self-assemble in the form dimeric/oligomeric complexes along the plasma membrane. Due to the molecular interactions they participate, GPCRs can potentially provide the framework for discriminating a wide variety of intercellular signals, as based on some kind of combinatorial receptor codes. GPCRs can in fact transduce signals from the external milieu by modifying the activity of such intracellular proteins as adenylyl cyclases, phospholipases and ion channels via interactions with specific G-proteins. However, in spite of (...)
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