I offer an analysis of the Principle of Sufficient Reason and its relevancy for the scientific endeavour. I submit that the world is not, and cannot be, rational—only some brained beings are. The Principle of Sufficient Reason is not a necessary truth nor a physical law. It is just a guiding metanomological hypothesis justified a posteriori by its success in helping us to unveil the mechanisms that operate in Nature.

I offer a formal ontological theory where the basic building blocks of the world are timeless events. The composition of events results in processes. Spacetime emerges as the system of all events. Things are construed as bundles of processes. I maintain that such a view is in accord with General Relativity and offers interesting prospects for the foundations of classical and quantum gravity.