This paper deals with the reification of the concept of race in biomedical research. It combines philosophical analysis and a quantitative approach to investigate the ways in which the reification fallacy may occur in race research, thereby providing theoretical legitimacy to the misuse of scientific research. It examines the prevalence of obesity in the US and some African countries as an empirical case to guide a conceptual analysis. The paper suggests that, to avoid the reification of race, researchers need to (...) be more aware of the fact that continental genetic clusters do not necessarily correspond to the genotypic partitions of interest in therapeutic reaction or disease etiology, and need to take seriously the phenotypic variability of breeding populations within continents. (shrink)