Empirical success is a central criterion for scientific decision-making. Yet its understanding in philosophical studies of science deserves renewed attention: Should philosophers think differently about the advancement of science when they deal with the uncertainty of outcome in ongoing research in comparison with historical episodes? This paper argues that normative appeals to empirical success in the evaluation of competing scientific explanations can result in unreliable conclusions, especially when we are looking at the changeability of direction in ongoing investigations. The challenges (...) we encounter arise from the inherent dynamics of disciplinary and experimental objectives in research practice. In this paper we discuss how these dynamics inform the evaluation of empirical success by analyzing three of its requirements: data accommodation, instrumental reliability, and predictive power. We conclude that the assessment of empirical success in developing inquiry is set against the background of a model’s interactive success and prospective value in an experimental context. Our argument is exemplified by the analysis of an apparent controversy surrounding the model of a quantum nose in research on olfaction. Notably the public narrative of this controversy rests on a distorted perspective on measures of empirical success. (shrink)

Organisms' environments are thought to play a fundamental role in determining their fitness and hence in natural selection. Existing intuitive conceptions of environment are sufficient for biological practice. I argue, however, that attempts to produce a general characterization of fitness and natural selection are incomplete without the help of general conceptions of what conditions are included in the environment. Thus there is a "problem of the reference environment"—more particularly, problems of specifying principles which pick out those environmental conditions which determine (...) fitness. I distinguish various reference environment problems and propose solutions to some of them. While there has been a limited amount of work on problems concerning what I call "subenvironments", there appears to be no earlier work on problems of what I call the "whole environment". The first solution I propose for a whole environment problem specifies the overall environment for natural selection on a set of biological types present in a population over a specified period of time. The second specifies an environment relevant to extinction of types in a population; this kind of environment is especially relevant to certain kinds of long-term evolution. (shrink)

Leslie Graves, Barbara Horan and Alex Rosenberg (1999) have argued that the process of evolution is really deterministic, so we should be instrumentalists about our probabilistic evolutionary theory. I criticize the consistency of their view. I argue that because they are realists towards multiple theories (quantum mechanics and macrophysics) their arguments against realism for another scientific theory fail. The main point of this paper is critical, but in order to set up this criticism I explore the ramifications of realism for (...) multiple theories. Finally, I offer a brief metaphysical justification for realism about multiple theories. This view justifies realism for evolutionary theory, which has been defended by Robert Brandon and Scott Carson (1996). (shrink)

Probability and indeterminism have always been core philosophical themes. This paper aims to contribute to understanding probability and indeterminism in biology. To provide the background for the paper, it will first be argued that an omniscient being would not need the probabilities of evolutionary theory to make predictions about biological processes. However, despite this, one can still be a realist about evolutionary theory, and then the probabilities in evolutionary theory refer to real features of the world. This prompts the question (...) of how to interpret biological probabilities which correspond to real features of the world but are in principle dispensable for predictive purposes. This paper will suggest three possible interpretations. The first interpretation is a propensity interpretation of kinds of systems. It will be argued that backward probabilities in biology do not present a problem for this propensity interpretation. The second interpretation is the frequency interpretation. Third, I will suggest Humean chances are a new interpretation of probability in evolutionary theory. Finally, this paper discusses Sansom’s argument that biological processes are indeterministic because probabilities in evolutionary theory refer to real features of the world. It will be argued that Sansom’s argument is not conclusive, and that the question whether biological processes are deterministic or indeterministic is still with us. (shrink)

John Beatty (1995) and Alexander Rosenberg (1994) have argued against the claim that there are laws in biology. Beatty's main reason is that evolution is a process full of contingency, but he also takes the existence of relative significance controversies in biology and the popularity of pluralistic approaches to a variety of evolutionary questions to be evidence for biology's lawlessness. Rosenberg's main argument appeals to the idea that biological properties supervene on large numbers of physical properties, but he also develops (...) case studies of biological controversies to defend his thesis that biology is best understood as an instrumental discipline. The present paper assesses their arguments. (shrink)

Since the last decades of the twentieth and the beginning of the twenty-first century, the use of metaphysics by philosophers when approaching conceptual problems in biology has increased. Some philosophers call this tendency in philosophy of biology ‘Metaphysics of Biology’. In this paper, I aim at characterizing Metaphysics of Biology by paying attention to the diverse ways philosophers use metaphysics when addressing conceptual problems in biology. I will claim that there are two different modes of doing Metaphysics of Biology, namely (...) Metaphysics for Biology and Metaphysics in Biology. (shrink)

In this paper I address the question of whether the probabilities that appear in models of stochastic gene expression are objective or subjective. I argue that while our best models of the phenomena in question are stochastic models, this fact should not lead us to automatically assume that the processes are inherently stochastic. After distinguishing between models and reality, I give a brief introduction to the philosophical problem of the interpretation of probability statements. I argue that the objective vs. subjective (...) distinction is a false dichotomy and is an unhelpful distinction in this case. Instead, the probabilities in our models of gene expression exhibit standard features of both objectivity and subjectivity. (shrink)

Es una opinión extendida que la teoría de la selección natural, tal como fue formulada originalmente por Darwin de manera “cualitativa”, ha sido reemplazada por una versión cuantitativa superior, brindada por la genética de poblaciones. En este artículo se discute contra esa tesis, sosteniendo en cambio que ambas teorías son complementarias, no sucesivas. Para ello, se introduce una línea de argumentación novedosa, que toma su inspiración en la crítica al “inductivismo estrecho” de Hempel. Se sostiene que los genetistas de poblaciones (...) serían incapaces de aplicar exitosamente su teoría sin hipótesis “ecológicas” preconcebidas, provenientes de la teoría darwiniana, que permitan particionar a la población en rasgos selectivamente relevantes. Se enfatiza además que la falla en notar este punto se debe a una mala comprensión de la estructura de la teoría darwiniana y de su ley o principio fundamental. A la luz de una mejor reconstrucción de dicho principio, se reexamina en mayor detalle la relación existente entre ambas teorías. (shrink)

In Social Empiricism, Miriam Solomon proposes a via media between traditional philosophical realism and social construction of scientific knowledge, but ignores a large body of historical literature that has attempted to plough just that path. She also proposes a standard for normatively appropriate consensus that, arguably, no theory in the history of science has ever achieved, including her own ideal type—plate tectonics. And while valorizing dissent, she fails to consider how dissent has been used in recent decades as a political (...) tool to challenge scientific evidence on diverse issues, including the link between tobacco and cancer and the reality of anthropogenic global warming. (shrink)

A long-standing debate has dominated systematic biology and the ontological commitments made by its theories. The debate has contrasted individuals and the part – whole relationship with classes and the membership relation. This essay proposes to conceptualize the hierarchy of higher taxa is terms of a hierarchy of homeostatic property cluster natural kinds (biological species remain largely excluded from the present discussion). The reference of natural kind terms that apply to supraspecific taxa is initially fixed descriptively; the extension of those (...) natural kind terms is subsequently established by empirical investigation. In that sense, classification precedes generalization, and description provides guidance to empirical investigation. The reconstruction of a hierarchy of (homeostatic property cluster) natural kinds is discussed in the light of cladistic methods of phylogeny reconstruction. (shrink)

Introduces a series of articles which deals with the relationship between history of science and philosophy of science.; Introduces a series of articles which deals with the relationship between history of science and philosophy of science.