This study examines how a Purkinje cell receives its appropriate olivary error signal during the learning of compound movements. We suggest that the Purkinje cell only reinforces those target pyramidal cells which already participate in the movement, subsequently reducing any repeated error signal, such as its own climbing fiber input, [simpson et al.; smith].

The views of Houk et al., Smith, and Thach on the role of cerebellum in movement control differ substantially, but all three are flawed by the false reasoning that because information passes from the cerebellum to movements the cerebellum must be a movement controller, or a part of one. The divergent and less than compelling ideas expressed by these leading cerebellar theorists epitomize the fruitlessness of this paradigm, and signal the need for a change. [HOUK et al.; SMITH; THACH].

Bioimage analysis plays a critical role in extracting information from biological images, enabling deeper insights into cellular structures and processes. The integration of machine learning and deep learning techniques has revolutionized the field, enabling the automated, reproducible, and accurate analysis of biological images. Here, we provide an overview of the history and principles of machine learning and deep learning in the context of bioimage analysis. We discuss the essential steps of the bioimage analysis workflow, emphasizing how machine learning and deep (...) learning have improved preprocessing, segmentation, feature extraction, object tracking, and classification. We provide examples that showcase the application of machine learning and deep learning in bioimage analysis. We examine user‐friendly software and tools that enable biologists to leverage these techniques without extensive computational expertise. This review is a resource for researchers seeking to incorporate machine learning and deep learning in their bioimage analysis workflows and enhance their research in this rapidly evolving field. (shrink)

This chapter offers a brief characterization of creativity, followed by a review of some of the reasons people have been skeptical about the possibility of explaining creativity. It surveys some of the recent work on creativity that is naturalistic in the sense that it presumes creativity is natural, as opposed to magical, occult, or supernatural, and is therefore amenable to scientific inquiry. The chapter divides into two categories. The broader category is empirical philosophy, which draws on empirical research while addressing (...) questions that have traditionally been regarded as philosophical. The second category is experimental philosophy, a special branch of empirical philosophy in which experiments are designed by philosophers with the explicit purpose of addressing philosophical questions. This categorization is admittedly somewhat artificial, but it is a familiar one in the prevailing division of intellectual labor, and it will be a useful organizational tool for the chapter. (shrink)

In the behavioral literature on human movement, a distinction is made between the learning of parameters and the learning of new movement forms or topologies. Whereas the target articles by Thach, Smith, and Houk et al. provide evidence for cerebellar involvement in parametrization learning and adaptation, the evidence in favor of its involvement in the generation of new movement patterns is less straightforward. A case is made for focusing more attention on the latter issue in the future. This would directly (...) help to bridge the gap between current neurophysiological approaches to the role of the cerebellum and the behavioral expressions of human motor learning, [HOUK et al.; SMITH; THACH]. (shrink)

What is Computational Intelligence (CI) and what are its relations with Artificial Intelligence (AI)? A brief survey of the scope of CI journals and books with ``computational intelligence'' in their title shows that at present it is an umbrella for three core technologies (neural, fuzzy and evolutionary), their applications, and selected fashionable pattern recognition methods. At present CI has no comprehensive foundations and is more a bag of tricks than a solid branch of science. The change of focus from methods (...) to challenging problems is advocated, with CI defined as a part of computer and engineering sciences devoted to solution of non-algoritmizable problems. In this view AI is a part of CI focused on problems related to higher cognitive functions, while the rest of the CI community works on problems related to perception and control, or lower cognitive functions. Grand challenges on both sides of this spectrum are addressed. (shrink)

The purpose of this article is to show why consciousness and thought are not manifested in digital computers. Analyzing the rationale for claiming that the formal manipulation of physical symbols in Turing machines would emulate human thought, the article attempts to show why this proved false. This is because the reinterpretation of designation and meaning to accommodate physical symbol manipulation eliminated their crucial functions in human discourse. Words have denotations and intensional meanings because the brain transforms the physical stimuli received (...) from the microworld into a qualitative, macroscopic representation for consciousness. Lacking this capacity as programmed machines, computers have no representations for their symbols to designate and mean. Unlike human beings in which consciousness and thought, with their inherent content, have emerged because of their organic natures, serial processing computers or parallel distributed processing systems, as programmed electrical machines, lack these causal capacities. (shrink)