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  1. Calculating life? Duelling discourses in interdisciplinary systems biology.Jane Calvert & Joan H. Fujimura - 2011 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 42 (2):155-163.
    A high profile context in which physics and biology meet today is in the new field of systems biology. Systems biology is a fascinating subject for sociological investigation because the demands of interdisciplinary collaboration have brought epistemological issues and debates front and centre in discussions amongst systems biologists in conference settings, in publications, and in laboratory coffee rooms. One could argue that systems biologists are conducting their own philosophy of science. This paper explores the epistemic aspirations of the field by (...)
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  • Extending the Argument from Unconceived Alternatives: Observations, Models, Predictions, Explanations, Methods, Instruments, Experiments, and Values.Darrell P. Rowbottom - 2016 - Synthese (10).
    Stanford’s argument against scientific realism focuses on theories, just as many earlier arguments from inconceivability have. However, there are possible arguments against scientific realism involving unconceived (or inconceivable) entities of different types: observations, models, predictions, explanations, methods, instruments, experiments, and values. This paper charts such arguments. In combination, they present the strongest challenge yet to scientific realism.
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  • Corroboration and auxiliary hypotheses: Duhem’s thesis revisited.Darrell Patrick Rowbottom - 2010 - Synthese 177 (1):139-149.
    This paper argues that Duhem’s thesis does not decisively refute a corroboration-based account of scientific methodology (or ‘falsificationism’), but instead that auxiliary hypotheses are themselves subject to measurements of corroboration which can be used to inform practice. It argues that a corroboration-based account is equal to the popular Bayesian alternative, which has received much more recent attention, in this respect.
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  • Two Impossibility Results for Measures of Corroboration.Jan Sprenger - 2018 - British Journal for the Philosophy of Science 69 (1):139--159.
    According to influential accounts of scientific method, such as critical rationalism, scientific knowledge grows by repeatedly testing our best hypotheses. But despite the popularity of hypothesis tests in statistical inference and science in general, their philosophical foundations remain shaky. In particular, the interpretation of non-significant results—those that do not reject the tested hypothesis—poses a major philosophical challenge. To what extent do they corroborate the tested hypothesis, or provide a reason to accept it? Popper sought for measures of corroboration that could (...)
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  • The Role of Hypotheses in Biomechanical Research.Darrell Patrick Rowbottom & R. Mcneill Alexander - 2012 - Science in Context 25 (2):247-262.
    ArgumentThis paper investigates whether there is a discrepancy between stated and actual aims in biomechanical research, particularly with respect to hypothesis testing. We present an analysis of one hundred papers recently published inThe Journal of Experimental BiologyandJournal of Biomechanics, and examine the prevalence of papers which have hypothesis testing as a stated aim, contain hypothesis testing claims that appear to be purely presentational, and have exploration as a stated aim. We found that whereas no papers had exploration as a stated (...)
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