People engaged in international research projects – whether sponsors, researchers or participants – have different cultural and religious backgrounds. This can lead to quandaries over whose values should dictate the ethical basis for research. This paper addresses this issue by claiming that four core values are integral to the nature and justification of valid research and that to have integrity researchers must be committed to these values. Since the values are not specific to any particular culture or religion they constitute (...) a neutral ethical framework for the conduct of international research. It then claims that if researchers understand these values they can take responsibility for applying them to their own situation. This can help overcome problems which currently arise when researchers are not certain what to do because the specific ethical requirements of sponsors would be impractical or damaging if implemented in the circumstances in which the researchers operate. Finally, it is suggested that the four values outlined in the paper may be a basis for further work – such as developing awareness training and evolving guidance for specialist areas of research. (shrink)