Contemporary genetic and biomedical research on race and ethnicity has reignited the debate over the biological significance of these categories. This article provides an overview of the critical literature concerning the categorization of Hispanic and Hispanic populations within these research programs. More specifically, this article focuses on issues regarding: The conceptualization of Hispanic identity, issues of data collection and generalization (e.g., the use of a specific Hispanic nationality as a stand‐in for all Hispanics), the tension between social and biological classifications (...) of ethnic populations, and the social, political, and scientific implications of genetic research for Latin America. (shrink)