The following books have been received and many of them are still available for review. Interested reviewers please contact the reviews editor: [email protected], P. 2018. Philosophy in the H...

Optogenetics is an invasive neuromodulation technology involving the use of light to control the activity of individual neurons. Even though optogenetics is a relatively new neuromodulation tool whose various implications have not yet been scrutinized, it has already been approved for its first clinical trials in humans. As optogenetics is being intensively investigated in animal models with the aim of developing novel brain stimulation treatments for various neurological and psychiatric disorders, it appears crucial to consider both the opportunities and dangers (...) such therapies may offer. In this review, we focus on the memory-modifying potential of optogenetics, investigating what it is capable of and how it differs from other memory modification technologies. We then outline the safety challenges that need to be addressed before optogenetics can be used in humans. Finally, we re-examine crucial neuroethical concerns expressed in regard to other MMTs in the light of optogenetics and address those that appear to be unique to the memory-modifying potential of optogenetic technology. (shrink)

Does consciousness collapse the quantum wave function? This idea was taken seriously by John von Neumann and Eugene Wigner but is now widely dismissed. We develop the idea by combining a mathematical theory of consciousness (integrated information theory) with an account of quantum collapse dynamics (continuous spontaneous localization). Simple versions of the theory are falsified by the quantum Zeno effect, but more complex versions remain compatible with empirical evidence. In principle, versions of the theory can be tested by experiments with (...) quantum computers. The upshot is not that consciousness-collapse interpretations are clearly correct, but that there is a research program here worth exploring. (shrink)

When does a human being cease to exist? For millennia, the answer to this question had remained largely unchanged: death had been diagnosed when heartbeat and breathing were permanently absent. Only comparatively recently, in the 1950s, rapid developments in intensive-care medicine called into question this widely accepted criterion. What had previously been deemed a permanent cessation of vital functions suddenly became reversible. -/- A new criterion of death was needed. It was suggested that the destruction of the brain could indicate (...) the death of the organism in the presence of external life support. Soon the so-called brain death became the new worldwide standard. In recent years, however, doubts about this neurological criterion have been growing. Is brain death really our death? -/- This is the question that this thesis seeks to answer. To this end, we shall connect the medical debate about the definition of death to the philosophical debate about personal identity. While we will find that the destruction of its brain does in fact not correspond to an organism’s death, we shall also ask whether the assumption that we are essentially organisms is correct. May brain death be the ceasing to exist of a different entity? -/- Substituting clinical case reports and considerations about human physiology for the use of thought experiments, the thesis takes a novel and philosophically unconventional approach to the problem of what we essentially are. We shall analyse various pathological conditions and their respective effects on the bodily and mental characteristics of our existence. We will conclude that brain death is indeed our death – but for reasons entirely different from those cited in the original justification of this criterion. (shrink)

Co-Directors: Alexander Pruss & Tim O’Connor Committee: C. Stephen Evan’s, Todd Buras, -/- The current state of consciousness research is at an impasse. Neuroscience faces a variety of recalcitrant problems regarding the neurobiological binding together of states of consciousness. Philosophy faces the combination problem, that of holistically unifying phenomenal consciousness. In response, I argue that these problems all result from a naturalistic assumption that subjects of consciousness are built up out of distinct physical parts. I begin by developing a Husserlian (...) mereology of part-whole relations, which I apply to both an ontology of the holistic unity of the subjects of consciousness and the holistic unity of phenomenal consciousness itself. After a detailed analysis of the ontology and neuroscience of phenomenally unified consciousness, I argue against the three major naturalist views: physicalism, Russellian panpsychism, and emergentism. I develop various arguments demonstrating that these views each fail to account for the possibility of subjects of phenomenally unified consciousness. In the final chapter, I show how these arguments entail that the subject of phenomenal unity must be partless, must be a simple holistic unity. In turn, this provides a defense of substance dualism or at least something near enough. Given the widespread rejection of mind-body dualism, I answer certain neurological objections and conclude by sketching the details of an underexplored neo-Aristotelian form of substance dualism. I conclude that each of us, indeed every subject of phenomenally unified consciousness, is not made up of distinct parts. Not a brain. Not a body. Every embodied subject of phenomenally unified consciousness is a bodily soul. (shrink)