In his recent 2018 book, Resisting Scientific Realism, K. Brad Wray provides a detailed, full-fledged defense of anti-realism about science. In this paper, I argue against the two main claims that constitute Wray’s positive and novel argument for his position, viz., his suggested Darwinian-selectionist explanation of the success of science and his skepticism about unobservables based on radical theory change. My goal is not wholly negative though. Instead, I aim to identify the type of work that an anti-realist like Wray (...) would need to undertake in order to further substantiate their position, viz., taking a stance on inductive inference and support, and the type of realist and anti-realist positions that seem viable. (shrink)