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  1. Zombie ideas about early endosymbiosis: Which entry mechanisms gave us the “endo” in different endosymbionts?Dave Speijer - 2021 - Bioessays 43 (7):2100069.
    Recently, a review regarding the mechanics and evolution of mitochondrial fission appeared in Nature. Surprisingly, it stated authoritatively that the mitochondrial outer membrane, in contrast with the inner membrane of bacterial descent, was acquired from the host, presumably during uptake. However, it has been known for quite some time that this membrane was also derived from the Gram‐negative, alpha‐proteobacterium related precursor of present‐day mitochondria. The zombie idea of the host membrane still surrounding the endosymbiont is not only wrong, but more (...)
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  • Acid digestion and symbiont: Proton sharing at the origin of mitochondriogenesis?Mario Mencía - 2023 - Bioessays 45 (1):2200136.
    The initial relationships between organisms leading to endosymbiosis and the first eukaryote are currently a topic of hot debate. Here, I present a theory that offers a gradual scenario in which the origins of phagocytosis and mitochondria are intertwined in such a way that the evolution of one would not be possible without the other. In this scenario, the premitochondrial bacterial symbiont became initially associated with a protophagocytic host on the basis of cooperation to kill prey with symbiont‐produced toxins and (...)
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