This paper discusses two important emphases of epistemology – of virtue and vice epistemology in particular – one concerning agency and patiency, and the other concerning self-regard and other-regard. The paper offers, for the first time in the literature, a framework in which four types of epistemological work can be categorized according to their respective dual emphases: Type 1 (agent/self-regarding), Type 2 (agent/other-regarding), Type 3 (patient/self-regarding), and Type 4 (patient/other-regarding). The paper also shows how four ways of doing epistemology can (...) be categorized in terms of these four types and draws particular attention to one dubbed other-centering. (shrink)