Summary The mesotrons, or mesons, were the first elementary particles observed to be inherently unstable. This essay offers a reconstruction of the stream of researches related to mesotron decay, and examines how these researches shaped some of the basic concepts and practices of the emerging field of particle physics. Mass measurements could not settle the question of whether the mesons were a homogeneous kind of particles or an assortment of particles with different masses. The assumption of a single mass prevailed (...) not on experimental grounds but because the mesons were identified tentatively with the carriers of the nuclear force according to a theory formulated by Hideki Yukawa. The identification gained currency because it entailed the prediction of meson decay, and thereby upheld the promise of a unified explanation of nuclear and cosmic-ray phenomena. In turn, the observation of decay and the measurement of the mean lifetime created the conditions for investigating the nuclear interactions of mesons at rest. Interest in these interactions was heightened, immediately after WWII, by the prospect of building and using accelerators to acquire knowledge about fundamental nuclear processes. Using decay to study nuclear capture, however, led to the realization that there exist not only different kinds of mesons but also two nuclear forces. (shrink)