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The NIH Trials of Growth Hormone for Short Stature

Carol A. Tauer

IRB: Ethics & Human Research 16 (3):1 (1994)

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Ethical and Legal Issues in Enhancement Research on Human Subjects.Maxwell J. Mehlman, Jessica W. Berg, Eric T. Juengst & Eric Kodish - 2011 - Cambridge Quarterly of Healthcare Ethics 20 (1):30--45.details The United States, along with other nations and international organizations, has developed an elaborate system of ethical norms and legal rules to govern biomedical research using human subjects. These policies govern research that might provide direct health benefits to participants and research in which there is no prospect for participant health benefits. There has been little discussion, however, about how well these rules would apply to research designed to improve participants’ capabilities or characteristics beyond the goal of good health. When (...) Download Export citation Bookmark 5 citations
Response to Richard B. Miller's "Children, Ethics, and Modern Medicine". [REVIEW]Paul Lauritzen - 2006 - Journal of Religious Ethics 34 (1):151 - 161.details In this essay, Paul Lauritzen examines Richard B. Miller's liberal account of pediatric ethics by asking if the duty to promote a child's basic interests is substantial enough to secure the well-being of children. This question is raised in light of two case studies: daytime TV talk shows that broadcast interviews with sexually active children, and a medical study conducted to test the effect of growth hormone treatment on adult height in peripubertal children. In both cases, Lauritzen argues, children are (...) Download Export citation Bookmark 1 citation
An Ethical Justification for Research with Children.Ariella Binik - unknowndetails This thesis is a contribution to the ethical justification for clinical research with children. A research subject’s participation in a trial is usually justified, in part, by informed consent. Informed consent helps to uphold the moral principle of respect for persons. But children’s limited ability to make informed choices gives rise to a problem. It is unclear what, if anything, justifies their participation in research. Some research ethicists propose to resolve this problem by appealing to social utility, proxy consent, arguments (...) Download Export citation Bookmark 1 citation
Minimal risk revisited: the ethics of clinical research with children.Ariella Binik - unknowndetails One of the central problems concerning research with children is the delineation of appropriate levels of risk exposure. In the U.S. Code of Federal Regulations, the "minimal risk" concept serves as an anchoring measure for allowable risk. While the regulations sought to promote a balance between scientific advances and the protection of children's vulnerable status, ambiguities in the language of the regulations and the regulatory definition of "minimal risk" have given rise to a great deal of confusion. Research ethics boards (...) Download Export citation Bookmark 1 citation

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