This paper is a response to Christian Coseru, ‘The Middle Way to Reality: On Why I Am Not a Buddhist and Other Philosophical Curiosities.’ I address Coseru’s critical comments about naturalism, evolutionary psychology, scientific realism, and Madhyamaka philosophy. I argue that scientific naturalism is not the right framework for relating Buddhism to science; rather, the proper framework is the ethics of knowledge. I argue that Coseru’s defence of evolutionary psychology is unconvincing and rests on a misunderstanding of the issues concerning (...) the relations between evolutionary theory, evolutionary psychology, and Buddhist philosophy. Finally, I argue that there are considerable tensions between scientific realism and Buddhist philosophy. (shrink)