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  1. Think Pragmatically: Investigators’ Obligations to Patient-Subjects When Research is Embedded in Care.Stephanie R. Morain & Emily A. Largent - 2022 - American Journal of Bioethics 23 (8):10-21.
    Growing interest in embedded research approaches—where research is incorporated into clinical care—has spurred numerous studies to generate knowledge relevant to the real-world needs of patients and other stakeholders. However, it also has presented ethical challenges. An emerging challenge is how to understand the nature and extent of investigators’ obligations to patient-subjects. Prior scholarship on investigator duties has generally been grounded upon the premise that research and clinical care are distinct activities, bearing distinct duties. Yet this premise—and its corresponding implications—are challenged (...)
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