Physicalism as a worldview and framework for a mechanistic and materialist science seems not to have integrated the tectonic shift created by the rise of quantum physics with its notion of the personal equation of the observer. Psyche had been deliberately removed from a post-Enlightenment science. This paper explores a post-materialist science within a dual-aspect monist conception of nature in which both the mental and the physical exist in a relationship of complementarity so that they mutually exclude one another and (...) yet are together necessary to explain Reality while being irreducible to one another. Both mind and matter emerge from an underlying holistic domain known as the unus mundus in the Jung-Pauli formulation or as the analogous implicate order in the framing of physicist David Bohm and his colleagues. Kuhnian anomalies such as the role of reflective consciousness in evolution, and phenomena including so-called “near death experiences” (NDEs), are considered from the perspective of dual-aspect monism in conjunction with an emerging evolutionary panentheism. (shrink)