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  1. Circuits of Time: Enacting Postgenomics in Indigenous Australia.Henrietta Byrne, Emma Kowal, Jaya Keaney & Megan Warin - 2023 - Body and Society 29 (2):20-48.
    Some Indigenous Australians have embraced developmental origins of health and disease (DOHaD) and epigenetic discourses to highlight the legacies of slow violence in a settler colonial context. Despite important differences between Indigenous and scientific knowledges, some Indigenous scholars are positioning DOHaD and epigenetics as a resource to benefit their communities. This article argues that time plays a crucial role of brokering disparate knowledge spaces in Indigenous discourses of postgenomics, with both Indigenous cosmological frames and DOHaD/epigenetics centring a circular temporal model. (...)
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  • Biocircularities: New Formations of Embodied Time.Karen Jent & Branwyn Poleykett - 2023 - Body and Society 29 (2):3-19.
    In this introduction to the special section ‘Biocircularities: New Formations of Embodied Time’, we introduce the concept of ‘biocircularity’. Drawing on case studies from Senegal, Australia and the United States, we argue that (bio)circularities provides a new tool to understand transformations of embodiment and embodied time in response to rapid technoscientific, social and environmental change. We situate the potential of biocircularity by distinguishing the approach from cycles and ‘looping’. We lay out why we think biocircularity is an important concept now, (...)
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  • Disentangling life: Darwin, selectionism, and the postgenomic return of the environment.Maurizio Meloni - 2017 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 62:10-19.
    In this paper, I analyze the disruptive impact of Darwinian selectionism for the century-long tradition in which the environment had a direct causative role in shaping an organism’s traits. In the case of humans, the surrounding environment often determined not only the physical, but also the mental and moral features of individuals and whole populations. With its apparatus of indirect effects, random variations, and a much less harmonious view of nature and adaptation, Darwinian selectionism severed the deep imbrication of organism (...)
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  • Caring for biosocial complexity. Articulations of the environment in research on the Developmental Origins of Health and Disease.Michael Penkler - 2022 - Studies in History and Philosophy of Science Part A 93:1-10.
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  • The Temporal Politics of Placenta Epigenetics: Bodies, Environments and Time.Robbin Jeffries Hein & Martine Lappé - 2023 - Body and Society 29 (2):49-76.
    This article builds on feminist scholarship on new biologies and the body to describe the temporal politics of epigenetic research related to the human placenta. Drawing on interviews with scientists and observations at conferences and in laboratories, we argue that epigenetic research simultaneously positions placenta tissue as a way back into maternal and fetal bodies following birth, as a lens onto children’s future well-being, and as a bankable resource for ongoing research. Our findings reflect how developmental models of health have (...)
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  • Illuminating the ethical tensions in the obesity Canada website: a transdisciplinary social justice perspective.Deana Kanagasingam, Moss Norman & Laura Hurd - 2021 - Journal of Critical Realism 20 (5):474-490.
    Even though considerable resources have been allocated to the study of obesity, there is no consensus on its definition, causes, or solutions. Amidst ongoing debates over understandings of obesity, Obesity Canada (OC) was established to enhance the quality of life of Canadians with obesity through the advancement of anti-discrimination, policy change, and obesity prevention and treatment. Drawing upon a transdisciplinary social justice framework, we use critical thematic analysis to examine the OC website, which is the organization’s primary knowledge mobilization platform. (...)
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  • Von ‚Fehlanpassungen‘ und ‚metabolischen Ghettos‘: Zur Konzeptualisierung globaler Gesundheitsunterschiede im Feld der Developmental Origins of Health and Disease.Michael Penkler & Ruth Müller - 2018 - Berichte Zur Wissenschaftsgeschichte 41 (3):258-278.
    On ‘Mismatch’ and ‘Metabolic Ghettos:’ The Conceptualization of Global Health Differences in Research on the Developmental Origins of Health and Disease. Epigenetic approaches to human health have received growing attention in the past two decades. They allow to view the development of human organisms as plastic, i.e. as open to influences from the social and material environment such as nutrition, stress, and trauma. This has lent new credence to approaches in biomedicine that aim to draw attention to the importance of (...)
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  • Drugs, Brains and Other Subalterns: Public Debate and the New Materialist Politics of Addiction.Mats Ekendahl, Kylie Valentine & Suzanne Fraser - 2018 - Body and Society 24 (4):58-86.
    Over the last few decades feminists, science and technology studies scholars and others have grappled with how to take materiality into account in understanding social practices, subjectivity and events. One key area for these debates has been drug use and addiction. At the same time, neuroscientific accounts of drug use and addiction have also arisen. This development has attracted criticism as simplistically reinstating material determinism. In this article we draw on 80 interviews with health professionals directly involved in drug-related public (...)
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  • Postgenomic understandings of fatness and metabolism.Azita Chellappoo - 2024 - History and Philosophy of the Life Sciences 46 (4):1-23.
    Abstract‘Obesity’ has, for decades, been a subject of intense scientific and public interest, and remains a key target for postgenomic science. I examine the emergence of determinism in research into ‘obesity’ in the postgenomic field of metabolomics. I argue that determinism appears in metabolomics research in two ways: firstly, fragmentation and narrow construal of the environment is evident in metabolomics studies on weight loss interventions, resulting in particular features of the environment (notably, dietary intake) having outsized influence while the wider (...)
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  • Can you remember silence? Epigenetic memory and reversibility as a site of intervention.Stephanie Lloyd, Pierre-Eric Lutz & Chani Bonventre - 2023 - Bioessays 45 (7):2300019.
    Just over 20 years ago, molecular biologists Leonie Ringrose and Renato Paro published an article with a provocative title, “Remembering Silence”, in BioEssays. The article focused on how epigenetic elements could return to their silent state, operationally defined as their epigenetic status before their modulation by experimental or environmental factors. Though Ringrose and Paro's article was on fruit flies and factors affecting embryological growth, the article asked a question of considerable importance to rapidly expanding research in neuroepigenetics on the correlation (...)
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  • A Postgenomic Body: Histories, Genealogy, Politics.Maurizio Meloni - 2018 - Body and Society 24 (3):3-38.
    This article sets the stage for a genealogy of the postgenomic body. It starts with the current transformative views of epigenetics and microbiomics to offer a more pluralistic history in which the ethical problem of how to live with a permeable body – that is plasticity as a form of life – is pervasive in traditions pre-dating and coexisting with modern biomedicine (particularly humoralism in its several ramifications). To challenge universalizing narratives, I draw on genealogical method to illuminate the unequal (...)
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  • Where organisms meet the environment.Jan Baedke & Tatjana Buklijas - 2023 - Studies in History and Philosophy of Science Part A 99 (C):4-9.
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  • The Politics of Postgenomic Reproduction: Exploring Pregnant Narratives from within a Clinical Trial.Natali Valdez - 2022 - Science, Technology, and Human Values 47 (6):1205-1230.
    There are more large-scale pregnancy trials that implement lifestyle interventions than ever before; yet, there is a dearth of information on pregnant peoples’ experiences in such trials. Contemporary lifestyle pregnancy trials draw on epigenetics and DOHaD research to design and justify prenatal interventions on the material environment to reduce health risks in future generations. This article draws on ethnographic data from a prenatal trial in the United Kingdom and focuses specifically on the experiences of pregnant participants during the intervention phase. (...)
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