This paper examines the ontological and epistemological implications of artificial intelligence (AI) through posthumanist philosophy, integrating the works of Deleuze, Foucault, and Haraway with contemporary computational methodologies. It introduces concepts such as negative augmentation, praxes of revealing, and desedimentation, while extending ideas like affirmative cartographies, ethics of alterity, and planes of immanence to critique anthropocentric assumptions about identity, cognition, and agency. By redefining AI systems as dynamic assemblages emerging through networks of interaction and co-creation, the paper challenges traditional dichotomies such (...) as human versus machine and subject versus object. Bridging analytic and continental philosophical traditions, the analysis unites formal tools like attribution analysis and causal reasoning with the interpretive and processual methodologies of continental thought. This synthesis deepens the understanding of AI’s epistemic and ethical dimensions, expanding philosophical inquiry while critiquing anthropocentrism in AI design. The paper interrogates the spatial foundations of AI, contrasting Euclidean and non-Euclidean frameworks to examine how optimization processes and adversarial generative models shape computational epistemologies. Critiquing the reliance on Euclidean spatial assumptions, it positions alternative geometries as tools for modeling complex, recursive relationships. Furthermore, the paper addresses the political dimensions of AI, emphasizing its entanglements with ecological, technological, and sociopolitical systems that perpetuate inequality. Through a politics of affirmation and intersectional approaches, it advocates for inclusive frameworks that prioritize marginalized perspectives. The concept of computational qualia is also explored, highlighting how subjective-like dynamics emerge within AI systems and their implications for ethics, transparency, and machine perception. Finally, paper calls for a posthumanist framework in AI ethics and safety, emphasizing interconnectivity, plurality, and the transformative capacities of machine intelligence. This approach advances epistemic pluralism and reimagines the boundaries of intelligence in the digital age, fostering novel ontological possibilities through the co-creation of dynamic systems. (shrink)