_Locked_ and _unlocked_ strategies are illustrated in this article as concepts that deal with important cognitive aspects of deep learning systems. They indicate different inference routines that refer to poor (locked) to rich (unlocked) cases of creative production of creative cognition. I maintain that these differences lead to important consequences when we analyze computational deep learning programs, such as AlphaGo/AlphaZero, which are able to realize various types of abductive hypothetical reasoning. These programs embed what I call locked abductive strategies, so, (...) even if they present spectacular performances for example in games, they are characterized by poor types of hypothetical creative cognition insofar as they are constrained in what I call _eco-cognitive openness_. This openness instead characterizes unlocked human cognition that pertains to higher kinds of abductive reasoning, in both the creative and diagnostic cases, in which cognitive strategies are instead unlocked. This special kind of “openness” is physically rooted in the fundamental character of the human brain as an open system constantly coupled with the environment (that is, an “open” or “dissipative” system): its activity is the uninterrupted attempt to achieve the equilibrium with the environment in which it is embedded, and this interplay can never be switched off without producing severe damage to the brain. The brain cannot be conceived as deprived of its physical quintessence that is its openness. In the brain, contrary to the computational case, ordering is not derived from the outside thanks to what I have called in a recent book “computational domestication of ignorant entities”, but it is the direct product of an “internal” open dynamical process of the system. (shrink)