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  1. Fractured Symmetries: Information and Control Theory Perspectives on Mitochondrial Dysfunction.Rodrick Wallace - 2020 - Acta Biotheoretica 69 (3):277-301.
    Mitochondrial dysfunction underlies a vast array of chronic disorders across the life span. The asymptotic limit theorems of information and control theories, supplemented by symmetry-breaking phase transition arguments adapted from physical theory, give deep insight into canonical mechanisms of cognition and regulation associated with such dysfunction. The probability models studied here can provide a foundation for the development of statistical tools useful in clinical and public health address of those disorders.
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  • Major Transitions as Groupoid Symmetry-Breaking in Nonergodic Prebiotic, Biological and Social Information Systems.Rodrick Wallace - 2022 - Acta Biotheoretica 70 (4):1-20.
    We extend the comparatively simple processes of group symmetry-breaking in physical systems to groupoid/equivalence class phase transitions characterizing adiabatically, piecewise stationary, information transmission in prebiotic, biological, and social phenomena: High vs. Low probability paths $$\rightarrow$$ Interior and Exterior Interact $$\rightarrow$$ Multiple Interacting Tunable Workspaces Application to nonstationary processes seems possible via generalizations of the symmetry algebra, for example, to semigroupoids. The dynamic probability models explored here can be transformed into statistical tools for the analysis of real-time and other data across (...)
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