Due to the NP-hard nature, the permutation flowshop scheduling problem is a fundamental issue for Industry 4.0, especially under higher productivity, efficiency, and self-managing systems. This paper proposes an improved genetic-shuffled frog-leaping algorithm to solve the permutation flowshop scheduling problem. In the proposed IGSFLA, the optimal initial frog in the initialized group is generated according to the heuristic optimal-insert method with fitness constrain. The crossover mechanism is applied to both the subgroup and the global group to avoid the local optimal (...) solutions and accelerate the evolution. To evolve the frogs with the same optimal fitness more outstanding, the disturbance mechanism is applied to obtain the optimal frog of the whole group at the initialization step and the optimal frog of the subgroup at the searching step. The mathematical model of PFSSP is established with the minimum production cycle as the objective function, the fitness of frog is given, and the IGSFLA-based PFSSP is proposed. Experimental results have been given and analyzed, showing that IGSFLA not only provides the optimal scheduling performance but also converges effectively. (shrink)