Previous research has found that depression is characterised by biased processing of emotional information. Although most studies have examined cognitive biases in isolation, simultaneous examination of multiple biases is required to understand how they may interact and influence one another to produce depression vulnerability. In this study, the attention and memory biases of currently depressed, previously depressed, and never depressed women were examined using the same stimuli and a unified methodology. Participants viewed negative, positive, and neutral words while their eye (...) gaze was tracked and recorded. After a distraction task, participants completed an incidental recognition test that included words from the eye-tracking task and new words. The results supported the hypothesised mediation model for positive words: currently depressed women had a reduced attention bias for positive words and, in turn, had poorer memory for positive words relative to never depressed women. Previously depressed women, however, showed a lack of coherence between attention and memory biases for positive words. The groups did not differ in their attention or memory biases for negative words. The findings provide novel evidence in support of a causal link between the absence of protective attention and memory biases for positive information in clinical depression. (shrink)

Rumination has been linked to the onset and course of depression. Theoretical models and empirical evidence suggest that deficits controlling negative material in working memory underlie rumination. However, we do not know which component of cognitive control contributes most to rumination, and whether different components predict the more maladaptive versus the more adaptive forms of rumination. We aimed to advance theory and research by examining the contribution of different facets of cognitive control to the level and trajectory of brooding and (...) reflection. At baseline, participants completed three cognitive tasks that assessed their inhibition, shifting, and updating biases, respectively. Next, using experience sampling methodology, participants rated their level of rumination and negative affect nine times during the 48 h after their most stressful exam. At each time point, higher levels of brooding, but not reflection, predicted higher levels of negative affect at the next time point. Furthermore, several facets of shifting and inhibition, but not updating, predicted brooding immediately after the exam and its trajectory of change over 48 h. Additionally, difficulty inhibiting neutral words predicted both brooding and reflection. These findings inform theoretical models describing the role of cognitive control in brooding and reflection. (shrink)

Depression is a highly recurrent disorder with limited treatment alternatives for reducing risk of subsequent episodes. Acceptance and commitment therapy (ACT) and attention bias modification (ABM) separately have shown some promise in reducing depressive symptoms. This study investigates (a) if group-based ACT had a greater impact in reducing residual symptoms of depression over a 12-month follow-up than a control condition, and (b) if preceding ACT with ABM produced added benefits. This multisite study consisted of two phases. In phase 1, participants (...) with a history of depression, currently in remission (N= 244), were randomized to either receive 14 days of ABM or a control condition. In phase 2, a quasi- experimental design was adopted, and only phase-1 participants from the Sørlandet site (N= 124) next received an 8-week group-based ACT intervention. Self-reported and clinician-rated depression symptoms were assessed at baseline, immediately after phase 1 and at 1, 2, 6, and 12 months after the conclusion of phase 1. At 12-month follow-up, participants who received ACT exhibited fewer self-reported and clinician-rated depressive symptoms. There were no significant differences between ACT groups preceded by ABM or a control condition. There were no significant differences between ACT groups preceded by ABM or a control condition. Group-based ACT successfully decreased residual symptoms in depression over 12 months, suggesting some promise in preventing relapse. (shrink)

Ana García-Blanco (a,b), Manuel Perea (a) y Ladislao Salmerón (a) (a) ERI-Lectura, Universitat de València, España (b) Servicio de Psiquiatría, … Read More →.