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Language and Communication as Universal Requirements for Life

In Kolb Vera (ed.), Astrobiology: An Evolutionary Approach. CRC Press. pp. 349-370 (2014)

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  1. Quasispecies Productivity.Guenther Witzany - 2024 - The Science of Nature (Naturwissenschaften) 111:11.
    Abstract The quasispecies theory is a helpful concept in the explanation of RNA virus evolution and behaviour, with a relevant impact on methods used to fight viral diseases. It has undergone some adaptations to integrate new empirical data, especially the non-deterministic nature of mutagenesis, and the variety of behavioural motifs in cooperation, competition, communication, innovation, integration, and exaptation. Also, the consortial structure of quasispecies with complementary roles of memory genomes of minority populations better fits the empirical data than did the (...)
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  • That is life: communicating RNA networks from viruses and cells in continuous interaction.Guenther Witzany - 2019 - Annals of the New York Academy of Sciences:1-16.
    All the conserved detailed results of evolution stored in DNA must be read, transcribed, and translated via an RNAmediated process. This is required for the development and growth of each individual cell. Thus, all known living organisms fundamentally depend on these RNA-mediated processes. In most cases, they are interconnected with other RNAs and their associated protein complexes and function in a strictly coordinated hierarchy of temporal and spatial steps (i.e., an RNA network). Clearly, all cellular life as we know it (...)
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  • Artificial and Natural Genetic Information Processing.Guenther Witzany - 2017 - In Mark Burgin & Wolfgang Hoflkirchner (eds.), Information Studies and the Quest for Transdisciplinarity. New York, USA: World Scientific. pp. 523-547.
    Conventional methods of genetic engineering and more recent genome editing techniques focus on identifying genetic target sequences for manipulation. This is a result of historical concept of the gene which was also the main assumption of the ENCODE project designed to identify all functional elements in the human genome sequence. However, the theoretical core concept changed dramatically. The old concept of genetic sequences which can be assembled and manipulated like molecular bricks has problems in explaining the natural genome-editing competences of (...)
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  • The biocommunication method: On the road to an integrative biology.Witzany Guenther - 2016 - Communicative and Integrative Biology 9:e1164374.
    Although molecular biology, genetics, and related special disciplines represent a large amount of empirical data, a practical method for the evaluation and overview of current knowledge is far from being realized. The main concepts and narratives in these fields have remained nearly the same for decades and the more recent empirical data concerning the role of noncoding RNAs and persistent viruses and their defectives do not fit into this scenario. A more innovative approach such as applied biocommunication theory could translate (...)
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  • Two genetic codes: Repetitive syntax for active non-coding RNAs; non-repetitive syntax for the DNA archives.Witzany Guenther - 2017 - Communicative and Integrative Biology 10 (2):e1297352-1 - e1297352-12.
    Current knowledge of the RNA world indicates 2 different genetic codes being present throughout the living world. In contrast to non-coding RNAs that are built of repetitive nucleotide syntax, the sequences that serve as templates for proteins share—as main characteristics—a non-repetitive syntax. Whereas non-coding RNAs build groups that serve as regulatory tools in nearly all genetic processes, the coding sections represent the evolutionarily successful function of the genetic information storage medium. This indicates that the differences in their syntax structure are (...)
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  • Communication as the Main Characteristic of Life.Guenther Witzany - 2019 - In M. Kolb Vera (ed.), Handbook of Astrobiology. CrC Press. pp. 91-105.
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