The relationship between metacognition and mindreading was investigated by examining how well one can monitor their own learning compared to another person’s learning. Here, we used functional near-infrared spectroscopy to systematically investigate the brain area activation during metacognition and mindreading. The evidence indicated that metacognition and mindreading are underpinned by distinct neural systems. Metacognition is associated with activation in brain regions important for memory retrieval, such as the fusiform gyrus, while mindreading is associated with activation in brain regions important for (...) understanding and reasoning about others’ intentions, such as the right temporoparietal junction. (shrink)